Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1025201 | 0.77 | ALDH1A1 (0.36) | CYP1A2CYP2A6HTR2CALDH1A1CA1 | |
| Hydrochloric Acid SCHEMBL4634124 | 0.76 | ALDH1A1 (0.33) | CYP1A2CYP2A6HTR2CALDH1A1CA1 | |
| Hydrochloric Acid SCHEMBL7941112 | 0.76 | CYP1A2 (0.31) | CYP1A2CYP2A6HTR2CALDH1A1CA1 | |
| Hydrochloric Acid SCHEMBL1685540 | 0.74 | CYP1A2 (0.30) | CYP1A2CYP2A6HTR2C | |
| Hydrochloric Acid SCHEMBL2355025 | 0.74 | CYP1A2 (0.30) | CYP1A2CYP2A6HTR2C | |
| Hydrochloric Acid SCHEMBL9440324 | 0.73 | HTR2C (0.34) | CYP1A2CYP2A6HTR2CALDH1A1CA1 | |
| SCHEMBL8770717 | 0.73 | ALDH1A1 (0.32) | CYP1A2CYP2A6HTR2CALDH1A1CA1 | |
| SCHEMBL8024877 | 0.73 | CYP1A2 (0.32) | CYP1A2CYP2A6HTR2CALDH1A1CA1 | |
| SCHEMBL6454970 | 0.72 | HTR2C (0.31) | CYP1A2CYP2A6HTR2CALDH1A1CA1 | |
| Bromide SCHEMBL8034463 | 0.72 | ALDH1A1 (0.33) | CYP1A2CYP2A6HTR2CALDH1A1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5336746-A | Using a cycloalkadienylhafnium-alumoxane coordination catalyst and an alpha-olefin monomer; heat sealing agents having narrow molecular weight distribution yet low viscosity | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1994-08-09 | — | — | US | disclosed |