Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP5 | P45974 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | GCGR | P47871 | 5/20 | 0.35 |
| ▸ | ADCY6 | O43306 | 3/20 | 0.35 |
| ▸ | ADCY3 | O60266 | 3/20 | 0.35 |
| ▸ | ADCY9 | O60503 | 3/20 | 0.35 |
| ▸ | ADCY5 | O95622 | 3/20 | 0.35 |
| ▸ | ADCY8 | P40145 | 3/20 | 0.35 |
| ▸ | ADCY7 | P51828 | 3/20 | 0.35 |
| ▸ | ADCY2 | Q08462 | 3/20 | 0.35 |
| ▸ | ADCY1 | Q08828 | 3/20 | 0.35 |
| ▸ | ADCY4 | Q8NFM4 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3668173 | 0.93 | HSD17B10 (0.37) | USP5GCGRADCY6ADCY3ADCY9 | |
| SCHEMBL5569722 | 0.91 | HSD17B10 (0.36) | USP5GCGRADCY6ADCY3ADCY9 | |
| SCHEMBL3671962 | 0.88 | PTGS1 (0.34) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL3670931 | 0.81 | ALDH1A1 (0.41) | NR1H4EPHX2ADRB3 | |
| SCHEMBL3673110 | 0.79 | FFAR1 (0.34) | GCGRLMNAESR1ESR2FFAR1 | |
| SCHEMBL3674302 | 0.77 | ALDH1A1 (0.40) | L3MBTL1LMNACYP2C9AKR1C3ADRB3 | |
| SCHEMBL2637707 | 0.76 | ACE (0.53) | ACEFFAR1 | |
| SCHEMBL3673246 | 0.76 | MRGPRX4 (0.39) | NR1H4NFKB1MME | |
| SCHEMBL9808641 | 0.76 | NR1H4 (0.54) | L3MBTL1NR1H4EPHX2LMNAFFAR1 | |
| SCHEMBL4104840 | 0.75 | USP5 (0.39) | USP5ELANEL3MBTL1LMNAESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642296-B2 | 2-hydroxy-1-(4-hydroxymethyl-phenyl)-2-methyl-propan-1-one, have higher reactivity at the benzylic hydroxy group and do not have a tendency to yellowing; photocurable composition for pigmented or non-pigmented varnish surface coatings | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-01-05 | — | — | US | disclosed |
| US-20070240609-A1 | Photoinitiators | IGM GROUP B.V. (NL) | 2007-10-18 | — | — | US | disclosed |
| EP-1763499-B1 | NEW PHOTOINITIATORS | CIBA SC HOLDING AG (CH) | 2007-09-26 | — | — | EP | disclosed |
| EP-1763499-A1 | NEW PHOTOINITIATORS | CIBA SPECIALTY CHEMICALS HOLDING INC. Patent Departement (CH) | 2007-03-21 | — | — | EP | disclosed |
| WO-2005100292-A1 | NEW PHOTOINITIATORS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2005-10-27 | — | — | WO | disclosed |