Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.34 |
| ▸ | GCGR | P47871 | 5/20 | 0.33 |
| ▸ | ADCY6 | O43306 | 3/20 | 0.33 |
| ▸ | ADCY3 | O60266 | 3/20 | 0.33 |
| ▸ | ADCY9 | O60503 | 3/20 | 0.33 |
| ▸ | ADCY5 | O95622 | 3/20 | 0.33 |
| ▸ | ADCY8 | P40145 | 3/20 | 0.33 |
| ▸ | ADCY7 | P51828 | 3/20 | 0.33 |
| ▸ | ADCY2 | Q08462 | 3/20 | 0.33 |
| ▸ | ADCY1 | Q08828 | 3/20 | 0.33 |
| ▸ | ADCY4 | Q8NFM4 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | USP5 | P45974 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3668173 | 0.99 | HSD17B10 (0.37) | HSD17B10MGLLNR1H4GCGRADCY6 | |
| SCHEMBL3677451 | 0.91 | USP5 (0.38) | NR1H4GCGRADCY6ADCY3ADCY9 | |
| SCHEMBL3671962 | 0.85 | PTGS1 (0.34) | NR1H4GCGRADCY6ADCY3ADCY9 | |
| SCHEMBL10606212 | 0.78 | MAPT (0.51) | MGLLMAPK1ACEMAPTRXFP1 | |
| SCHEMBL1021016 | 0.78 | MAPT (0.51) | MGLLMAPK1ACEMAPTRXFP1 | |
| SCHEMBL3670931 | 0.78 | ALDH1A1 (0.41) | NR1H4EPHX2MAPT | |
| SCHEMBL3673110 | 0.77 | FFAR1 (0.34) | GCGR | |
| SCHEMBL7711934 | 0.76 | LTA4H (0.49) | MGLLMAPK1ACEMAPTRXFP1 | |
| SCHEMBL4425357 | 0.75 | LMNA (0.45) | MAPK1MAPT | |
| SCHEMBL3674302 | 0.74 | ALDH1A1 (0.40) | HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1763499-B1 | NEW PHOTOINITIATORS | CIBA SC HOLDING AG (CH) | 2007-09-26 | — | — | EP | disclosed |
| EP-1763499-A1 | NEW PHOTOINITIATORS | CIBA SPECIALTY CHEMICALS HOLDING INC. Patent Departement (CH) | 2007-03-21 | — | — | EP | disclosed |
| WO-2005100292-A1 | NEW PHOTOINITIATORS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2005-10-27 | — | — | WO | disclosed |