SCHEMBL3677566

SCHEMBL3677566

O=P(OCl)(Oc1ccccc1)ON1CCOCC1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.40
KMT2A Q03164 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA4 P22748 1/20 0.40
CA5A P35218 1/20 0.40
CA7 P43166 1/20 0.40
CA9 Q16790 1/20 0.40
CA5B Q9Y2D0 1/20 0.40
ALDH1A1 P00352 2/20 0.37
MAPT P10636 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
SRC P12931 1/20 0.36
POLB P06746 1/20 0.35
EPHX1 P07099 1/20 0.35
HSD17B10 Q99714 1/20 0.35
KDM4E B2RXH2 1/20 0.35
TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2852435 0.91 LMNA (0.44) LMNAKMT2ASMN1; SMN2CA12CA1
SCHEMBL3677562 0.82 LMNA (0.42) LMNAKMT2ASMN1; SMN2CA12CA1
SCHEMBL31249535 0.81 LMNA (0.41) LMNAKMT2ASMN1; SMN2CA12CA1
Tetrahydrofuran SCHEMBL28172868 0.80 SRC (0.41) KMT2ACA12CA1CA2CA4
SCHEMBL2858596 0.79 SRC (0.52) KMT2AMAPTNPSR1SRCKDM4E
SCHEMBL6060523 0.79 MMP1 (0.33) CA12CA7
SCHEMBL9782104 0.76 SRC (0.48) LMNAKMT2ACA12CA1CA2
SCHEMBL428879 0.75 SRC (0.54) LMNAKMT2ASRCKDM4ETDP1
SCHEMBL305506 0.75 SRC (0.54) LMNAKMT2ASRCKDM4ETDP1
Triphenyl Phosphate SCHEMBL22119479 0.73 SRC (0.52) LMNAKMT2ANPSR1SRCKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7691924-B2 Flame retardant thermoplastic resin composition CHEIL INDUSTRIES (KR) 2010-04-06 US disclosed
US-7550523-B2 Thermoplastic resin compositions containing mixtures of cyclic phosphazenes and phosphate ester morpholides CHEIL INDUSTRIES INC. (KR) 2009-06-23 US disclosed
US-20080182926-A1 Flame retardant thermoplastic resin composition CHEIL INDUSTRIES (KR) 2008-07-31 US disclosed
EP-1425347-B1 FLAME RETARDANT THERMOPLASTIC RESIN COMPOSITION CHEIL IND INC (KR) 2007-05-16 EP disclosed
US-20040249027-A1 Flame retardant thermoplastic resin composition CHEIL INDUSTRIES INC. (KR) 2004-12-09 US disclosed