Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2858596 | 0.92 | SRC (0.52) | SRCL3MBTL1TDP1KDM4ENPSR1 | |
| SCHEMBL2852435 | 0.84 | LMNA (0.44) | SRCL3MBTL1TDP1NPSR1MAPT | |
| SCHEMBL8466411 | 0.84 | SRC (0.44) | SRCL3MBTL1TDP1KDM4ENPSR1 | |
| SCHEMBL3677566 | 0.76 | LMNA (0.40) | SRCL3MBTL1TDP1KDM4ENPSR1 | |
| Triphenyl Phosphate SCHEMBL28557783 | 0.75 | SRC (0.64) | SRCL3MBTL1TDP1KDM4ENPSR1 | |
| Triphenyl Phosphate SCHEMBL483692 | 0.75 | SRC (0.64) | SRCL3MBTL1TDP1KDM4ENPSR1 | |
| Triphenyl Phosphate SCHEMBL28761613 | 0.75 | SRC (0.64) | SRCL3MBTL1TDP1KDM4ENPSR1 | |
| Triphenyl Phosphate SCHEMBL18116 | 0.75 | SRC (0.64) | SRCL3MBTL1TDP1KDM4ENPSR1 | |
| Triphenyl Phosphate SCHEMBL7202263 | 0.73 | SRC (0.70) | SRCL3MBTL1TDP1KDM4EMEN1 | |
| Triphenyl Phosphate SCHEMBL9622348 | 0.73 | SRC (0.70) | SRCL3MBTL1TDP1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992544-A | Intermediates for b-lactam antibiotics and b-lactamase inhibitor | UNIVERSITY OF NOTRE DAME DU LAC (US) | 1991-02-12 | — | — | US | disclosed |