SCHEMBL3677583

SCHEMBL3677583

CC/C=C/C=C/C1C(C(=O)OCC)C1(C)C

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.59
TSHR P16473 4/20 0.34
TDP1 Q9NUW8 4/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
NR1I2 O75469 1/20 0.34
PGR P06401 1/20 0.34
ADORA3 P0DMS8 1/20 0.34
PTGS2 P35354 1/20 0.34
PDE4D Q08499 1/20 0.34
HTT P42858 2/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 3/20 0.33
CYP3A4 P08684 2/20 0.33
ALOX15 P16050 1/20 0.33
HSD17B10 Q99714 1/20 0.33
TP53 P04637 1/20 0.32
CYP1A2 P05177 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3677585 1.00 LMNA (0.59) LMNATSHRTDP1MEN1KMT2A
SCHEMBL2167108 0.85 LMNA (0.41) LMNA
SCHEMBL2167105 0.85 LMNA (0.41) LMNA
SCHEMBL2167274 0.85 LMNA (0.41) LMNA
SCHEMBL2167111 0.85 LMNA (0.41) LMNA
SCHEMBL2167271 0.85 LMNA (0.41) LMNA
SCHEMBL2168541 0.80 LMNA (0.67) LMNATSHRTDP1MEN1KMT2A
SCHEMBL2168536 0.80 LMNA (0.67) LMNATSHRTDP1MEN1KMT2A
SCHEMBL3682711 0.80 LMNA (0.34) LMNA
SCHEMBL2170337 0.80 LMNA (0.67) LMNATSHRTDP1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7700799-B2 Method for producing (2-formyl-1-alkenyl) cyclopropane compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-04-20 US disclosed
US-20090137839-A1 METHOD FOR PRODUCING (2-FORMYL-1-ALKENYL) CYCLOPROPANE COMPOUND SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2009-05-28 US disclosed
US-7498459-B2 Method for producing (1-alkenyl)cyclopropane compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-03-03 US disclosed
US-20070197818-A1 Method for producing (1-alkenyl) cyclopropane compound SUMITOMO CHEMICAL COMPANY, LIMITED 2007-08-23 US disclosed
EP-1728781-A1 PROCESS FOR PRODUCTION OF (1-ALKENYL)CYCLOPROPANES Sumitomo Chemical Company, Limited (JP) 2006-12-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090137839-A1 METHOD FOR PRODUCING (2-FORMYL-1-ALKENYL) CYCLOPROPANE COMPOUND ACSL3, ACSL1, ARL1 LMNA 2696/4885TSHR 3074/4885TDP1 4458/4885
US-20070197818-A1 Method for producing (1-alkenyl) cyclopropane compound ACSL3, ARL1, ACSL1 LMNA 3763/4885TSHR 3751/4885TDP1 4490/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.