Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 16/20 | 0.76 |
| ▸ | RARG | P13631 | 16/20 | 0.76 |
| ▸ | RARA | P10276 | 14/20 | 0.76 |
| ▸ | RXRA | P19793 | 6/20 | 0.66 |
| ▸ | RXRB | P28702 | 3/20 | 0.51 |
| ▸ | RXRG | P48443 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL498220 | 0.86 | RARG (0.57) | RARBRARGRARARXRA | |
| SCHEMBL10040623 | 0.84 | RARG (0.53) | RARBRARGRARARXRA | |
| SCHEMBL497953 | 0.82 | RARB (0.87) | RARBRARGRARARXRARXRB | |
| SCHEMBL498280 | 0.81 | RARB (0.76) | RARBRARGRARARXRA | |
| SCHEMBL5846340 | 0.80 | RARB (0.77) | RARBRARGRARARXRARXRB | |
| SCHEMBL3677978 | 0.80 | RARB (1.00) | RARBRARGRARARXRARXRB | |
| SCHEMBL7873016 | 0.78 | RARB (0.83) | RARBRARGRARARXRARXRB | |
| SCHEMBL5846429 | 0.78 | RARB (0.83) | RARBRARGRARARXRARXRB | |
| SCHEMBL5846624 | 0.78 | RARB (0.83) | RARBRARGRARARXRARXRB | |
| SCHEMBL5846100 | 0.77 | RARG (1.00) | RARBRARGRARARXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1963249-B1 | BIPHENYL DERIVATIVES AS SELECTIVE AGONISTS OF GAMMA RAR RECEPTORS | GALDERMA RES & DEV (FR) | 2010-07-28 | — | — | EP | disclosed |
| EP-1963249-B1 | BIPHENYL DERIVATIVES AS SELECTIVE AGONISTS OF GAMMA RAR RECEPTORS | GALDERMA RES & DEV (FR) | 2010-07-28 | — | — | EP | disclosed |
| EP-1963249-A1 | BIPHENYL DERIVATIVES AS SELECTIVE AGONISTS OF GAMMA RAR RECEPTORS | Galderma Research & Development (FR) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007068579-A1 | BIPHENYL DERIVATIVES AS SELECTIVE AGONISTS OF GAMMA RAR RECEPTORS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2007-06-21 | — | — | WO | disclosed |