Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 17/20 | 0.76 |
| ▸ | RARG | P13631 | 16/20 | 0.76 |
| ▸ | RARA | P10276 | 14/20 | 0.76 |
| ▸ | RXRA | P19793 | 4/20 | 0.64 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.50 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL497825 | 0.87 | RARB (0.58) | RARBRARGRARARXRAABCB1 | |
| SCHEMBL497953 | 0.83 | RARB (0.87) | RARBRARGRARARXRA | |
| SCHEMBL5846043 | 0.82 | RARG (0.73) | RARBRARGRARARXRA | |
| SCHEMBL3677633 | 0.81 | RARB (0.76) | RARBRARGRARARXRA | |
| SCHEMBL7873016 | 0.78 | RARB (0.83) | RARBRARGRARARXRAABCB1 | |
| SCHEMBL5846624 | 0.78 | RARB (0.83) | RARBRARGRARARXRAABCB1 | |
| SCHEMBL5846429 | 0.78 | RARB (0.83) | RARBRARGRARARXRAABCB1 | |
| SCHEMBL3677978 | 0.78 | RARB (1.00) | RARBRARGRARARXRAABCB1 | |
| SCHEMBL5846340 | 0.78 | RARB (0.77) | RARBRARGRARARXRAABCB1 | |
| SCHEMBL2917374 | 0.78 | RARB (0.76) | RARBRARGRARARXRAABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106235-B2 | Biphenyl compound selective agonists of gamma RAR receptors | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2012-01-31 | — | — | US | claimed |
| EP-1963249-B1 | BIPHENYL DERIVATIVES AS SELECTIVE AGONISTS OF GAMMA RAR RECEPTORS | GALDERMA RES & DEV (FR) | 2010-07-28 | — | — | EP | claimed |
| US-20090036536-A1 | Biphenyl compound selective agonists of gamma RAR receptors | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2009-02-05 | — | — | US | claimed |
| US-8106235-B2 | Biphenyl compound selective agonists of gamma RAR receptors | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2012-01-31 | — | — | US | disclosed |
| US-8106235-B2 | Biphenyl compound selective agonists of gamma RAR receptors | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2012-01-31 | — | — | US | disclosed |
| US-8106235-B2 | Biphenyl compound selective agonists of gamma RAR receptors | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2012-01-31 | — | — | US | disclosed |
| EP-1963249-B1 | BIPHENYL DERIVATIVES AS SELECTIVE AGONISTS OF GAMMA RAR RECEPTORS | GALDERMA RES & DEV (FR) | 2010-07-28 | — | — | EP | disclosed |
| EP-1963249-B1 | BIPHENYL DERIVATIVES AS SELECTIVE AGONISTS OF GAMMA RAR RECEPTORS | GALDERMA RES & DEV (FR) | 2010-07-28 | — | — | EP | disclosed |
| US-20090036536-A1 | Biphenyl compound selective agonists of gamma RAR receptors | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2009-02-05 | — | — | US | disclosed |
| US-20090036536-A1 | Biphenyl compound selective agonists of gamma RAR receptors | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2009-02-05 | — | — | US | disclosed |
| US-20090036536-A1 | Biphenyl compound selective agonists of gamma RAR receptors | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2009-02-05 | — | — | US | disclosed |
| EP-1963249-A1 | BIPHENYL DERIVATIVES AS SELECTIVE AGONISTS OF GAMMA RAR RECEPTORS | Galderma Research & Development (FR) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007068579-A1 | BIPHENYL DERIVATIVES AS SELECTIVE AGONISTS OF GAMMA RAR RECEPTORS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2007-06-21 | — | — | WO | disclosed |
| WO-2007068579-A1 | BIPHENYL DERIVATIVES AS SELECTIVE AGONISTS OF GAMMA RAR RECEPTORS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2007-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036536-A1 | Biphenyl compound selective agonists of gamma RAR receptors | RARG, RARB, RARA | RARB 2/4885RARG 1/4885RARA 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.