Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 20/20 | 1.00 |
| ▸ | KDR | P35968 | 20/20 | 1.00 |
| ▸ | IGF1R | P08069 | 18/20 | 1.00 |
| ▸ | MST1R | Q04912 | 1/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL197995 | 1.00 | MET (1.00) | METKDRIGF1RMST1R | |
| SCHEMBL197994 | 1.00 | MET (1.00) | METKDRIGF1RMST1R | |
| SCHEMBL198254 | 0.95 | MET (1.00) | METKDRIGF1RMST1R | |
| SCHEMBL201155 | 0.95 | MET (1.00) | METKDRIGF1RMST1R | |
| SCHEMBL198255 | 0.95 | MET (1.00) | METKDRIGF1RMST1R | |
| SCHEMBL198122 | 0.94 | MET (0.90) | METKDRIGF1RMST1R | |
| SCHEMBL198123 | 0.94 | MET (0.90) | METKDRIGF1RMST1R | |
| SCHEMBL198489 | 0.94 | MET (0.90) | METKDRIGF1RMST1R | |
| SCHEMBL199486 | 0.94 | MET (0.91) | METKDRIGF1RMST1R | |
| SCHEMBL198488 | 0.94 | MET (0.90) | METKDRIGF1RMST1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2408300-B1 | AMINO ESTER DERIVATIVES, SALTS THEREOF AND METHODS OF USE | SUNSHINE LAKE PHARMA CO LTD (CN) | 2016-05-11 | — | — | EP | disclosed |
| US-8232294-B2 | Amino ester derivatives, sailts thereof and methods of use | Xi, Ning (US) | 2012-07-31 | — | — | US | disclosed |
| US-20100239576-A1 | AMINO ESTER DERIVATIVES, SAILTS THEREOF AND METHODS OF USE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2010-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100239576-A1 | AMINO ESTER DERIVATIVES, SAILTS THEREOF AND METHODS OF USE | SRC, BCAT1, BCAT2 | MET 185/4885KDR 958/4885IGF1R 599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.