Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | PTPRA | P18433 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MGMT | P16455 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL366526 | 0.93 | CNR1 (0.42) | FDPSPTPRAGRIN2DGRIN3BGRIN1 | |
| SCHEMBL1987162 | 0.76 | FDPS (0.45) | FDPSPTPRAGRIN2DGRIN3BGRIN1 | |
| SCHEMBL367309 | 0.74 | PTPRA (0.46) | FDPSPTPRAGRIN2DGRIN3BGRIN1 | |
| SCHEMBL366969 | 0.71 | FDPS (0.41) | FDPSPTPRAGRIN2DGRIN3BGRIN1 | |
| SCHEMBL14834767 | 0.70 | GRIN2D (0.46) | FDPSPTPRAGRIN2DGRIN3BGRIN1 | |
| SCHEMBL26109325 | 0.70 | PTPRA (0.53) | FDPSPTPRAGRIN2DGRIN3BGRIN1 | |
| SCHEMBL27657194 | 0.70 | FDPS (0.45) | FDPSPTPRAGRIN2DGRIN3BGRIN1 | |
| SCHEMBL27657192 | 0.70 | PTPRA (0.53) | FDPSPTPRAGRIN2DGRIN3BGRIN1 | |
| SCHEMBL10065055 | 0.69 | GSK3B (0.45) | KDM4EALDH1A1KMT2AL3MBTL1POLB | |
| SCHEMBL14917388 | 0.69 | GSK3B (0.45) | KDM4EALDH1A1KMT2AL3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009372-A2 | TRIAZOLIUM CARBENE CATALYSTS AND PROCESSES FOR ASYMMETRIC CARBON-CARBON BOND FORMATION | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2012-01-19 | — | — | WO | disclosed |