Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRA | P18433 | 1/20 | 0.46 |
| ▸ | FDPS | P14324 | 1/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MGMT | P16455 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1987162 | 0.84 | FDPS (0.45) | PTPRAFDPSGRIN2DGRIN3BGRIN1 | |
| SCHEMBL366969 | 0.79 | FDPS (0.41) | PTPRAFDPSGRIN2DGRIN3BGRIN1 | |
| SCHEMBL20609338 | 0.77 | PTPRA (0.50) | PTPRAFDPSGRIN2DGRIN3BGRIN1 | |
| SCHEMBL4967833 | 0.76 | PTPRA (0.53) | PTPRAFDPSGRIN2DGRIN3BGRIN1 | |
| SCHEMBL367767 | 0.74 | FDPS (0.41) | PTPRAFDPSGRIN2DGRIN3BGRIN1 | |
| SCHEMBL23791946 | 0.72 | ALDH1A1 (0.46) | PTPRAFDPSGRIN2DGRIN3BGRIN1 | |
| SCHEMBL1987785 | 0.71 | CNR1 (0.48) | CYP1A2CYP2D6TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL1378160 | 0.71 | ALDH1A1 (0.45) | PTPRAFDPSPOLBMGMTCYP1A2 | |
| SCHEMBL23765410 | 0.71 | GRIN2D (0.52) | PTPRAFDPSGRIN2DGRIN3BGRIN1 | |
| SCHEMBL20128507 | 0.71 | GRIN2D (0.52) | PTPRAFDPSGRIN2DGRIN3BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009372-A2 | TRIAZOLIUM CARBENE CATALYSTS AND PROCESSES FOR ASYMMETRIC CARBON-CARBON BOND FORMATION | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2012-01-19 | — | — | WO | disclosed |