Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | PTPRA | P18433 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | MGMT | P16455 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1987162 | 0.82 | FDPS (0.45) | FDPSPTPRAALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL367309 | 0.79 | PTPRA (0.46) | FDPSPTPRAALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL25706780 | 0.73 | ALDH1A1 (0.49) | FDPSPTPRAALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL104860 | 0.72 | GRIN2D (0.55) | FDPSPTPRAALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL18622385 | 0.72 | GRIN2D (0.59) | FDPSPTPRAALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL367767 | 0.71 | FDPS (0.41) | FDPSPTPRAALDH1A1GRIN2DGRIN3B | |
| Ammonia Solution, Strong SCHEMBL5620498 | 0.70 | GRIN2D (0.53) | FDPSPTPRAALDH1A1CYP1A2CYP2C19 | |
| Hydrochloric Acid SCHEMBL28948556 | 0.70 | GRIN2D (0.53) | FDPSPTPRAALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL27748422 | 0.70 | PTPRA (0.53) | FDPSPTPRAALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL14917161 | 0.69 | CPA1 (0.49) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009372-A2 | TRIAZOLIUM CARBENE CATALYSTS AND PROCESSES FOR ASYMMETRIC CARBON-CARBON BOND FORMATION | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2012-01-19 | — | — | WO | disclosed |