Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL340733 | 0.78 | — | — | |
| SCHEMBL1780756 | 0.77 | — | — | |
| SCHEMBL15624099 | 0.77 | TSHR (0.37) | TSHRALDH1A1HPGDADRB2ADRB1 | |
| SCHEMBL8462442 | 0.75 | ADRB2 (0.38) | TSHRALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL537821 | 0.74 | TSHR (0.38) | TSHRALDH1A1HPGDADRB2ADRB1 | |
| SCHEMBL7628200 | 0.73 | CYP3A4 (0.37) | TSHRALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL16189809 | 0.72 | TSHR (0.33) | TSHRALDH1A1HPGD | |
| SCHEMBL27510128 | 0.72 | TSHR (0.37) | TSHRALDH1A1HPGD | |
| SCHEMBL5029913 | 0.70 | TSHR (0.39) | TSHRHPGDADRB2ADRB1ADRB3 | |
| SCHEMBL449530 | 0.69 | ADRB2 (0.41) | TSHRALDH1A1HPGDADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1398353-B1 | THERMOPLASTIC RESIN COMPOSITION | KANEKA CORP (JP) | 2010-10-13 | — | — | EP | disclosed |
| US-7282535-B2 | Thermoplastic resin composition | KANEKA CORPORATION (JP) | 2007-10-16 | — | — | US | disclosed |
| US-20040147674-A1 | Thermoplastic resin composition | KANEKA CORPORATION (JP) | 2004-07-29 | — | — | US | disclosed |
| EP-1398353-A1 | THERMOPLASTIC RESIN COMPOSITION | Kaneka Corporation (JP) | 2004-03-17 | — | — | EP | disclosed |