SCHEMBL537821

SCHEMBL537821

C=CC([SiH3])(OCCCC)OCCCC

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.38
HPGD P15428 1/20 0.38
ALDH1A1 P00352 1/20 0.33
ADRB2 P07550 1/20 0.33
ADRB1 P08588 1/20 0.33
ADRB3 P13945 1/20 0.33
ATM Q13315 1/20 0.31
CYP3A4 P08684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7935122 0.93 TSHR (0.34) TSHRHPGDALDH1A1
SCHEMBL7937308 0.91 TSHR (0.38) TSHRHPGD
SCHEMBL3675609 0.86
SCHEMBL339298 0.75
SCHEMBL1782718 0.74
SCHEMBL12826538 0.74 TSHR (0.39) TSHRHPGDALDH1A1ADRB2ADRB1
SCHEMBL3677726 0.74 TSHR (0.36) TSHRHPGDALDH1A1ADRB2ADRB1
SCHEMBL28918138 0.74 HPGD (0.32) TSHRHPGD
SCHEMBL449530 0.72 ADRB2 (0.41) TSHRHPGDALDH1A1ADRB2ADRB1
SCHEMBL3886637 0.70 ADRB2 (0.39) TSHRALDH1A1ADRB2ADRB1ADRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150244026-A1 LITHIUM-ION SECONDARY BATTERY AND FORMULA FOR GEL ELECTROLYTE THEREOF DONGGUAN AMPEREX TECHNOLOGY LIMITED (CN) 2015-08-27 US claimed
US-9074032-B2 Membranes based on polyvinyl alcohol WACKER CHEMIE AG (DE) 2015-07-07 US claimed
EP-2414411-B1 MEMBRANES BASED ON POLYVINYL ALCOHOL WACKER CHEMIE AG (DE) 2013-02-20 EP claimed
US-20120031843-A1 Membranes based on polyvinyl alcohol WACKER CHEMIE AG (DE) 2012-02-09 US claimed
CN-214957015-U Lithium ion battery preparation system 沁新集团(天津)新能源技术研究院有限公司 2021-11-30 CN disclosed
CN-113161621-A Preparation method of lithium ion battery 沁新集团(天津)新能源技术研究院有限公司 2021-07-23 CN disclosed
US-20150244026-A1 LITHIUM-ION SECONDARY BATTERY AND FORMULA FOR GEL ELECTROLYTE THEREOF DONGGUAN AMPEREX TECHNOLOGY LIMITED (CN) 2015-08-27 US disclosed
US-9074032-B2 Membranes based on polyvinyl alcohol WACKER CHEMIE AG (DE) 2015-07-07 US disclosed
EP-2414411-B1 MEMBRANES BASED ON POLYVINYL ALCOHOL WACKER CHEMIE AG (DE) 2013-02-20 EP disclosed
US-20120031843-A1 Membranes based on polyvinyl alcohol WACKER CHEMIE AG (DE) 2012-02-09 US disclosed
EP-2414411-A2 MEMBRANES BASED ON POLYVINYL ALCOHOL Wacker Chemie AG (DE) 2012-02-08 EP disclosed
EP-1398353-B1 THERMOPLASTIC RESIN COMPOSITION KANEKA CORP (JP) 2010-10-13 EP disclosed
EP-0135923-B1 PRODUCTION OF WATER-CURABLE, SILANE MODIFIED THERMOPLASTIC POLYMERS UNION CARBIDE CORPORATION (US) 1989-09-20 EP disclosed
US-4767820-A HYDROLYZABLE, PENDANT SILANE MOIETIES ON HOMO- OR COPOLYMER OF AN OLEFIN OR DIOLEFIN UNION CARBIDE CORPORATION (US) 1988-08-30 US disclosed
US-4753993-A WATER CURABLE ETHYLENE POLYMERS HAVING PENDANT HYDROLZABLE SILANE GROUPS UNION CARBIDE CORPORATION (US) 1988-06-28 US disclosed
US-4707520-A Composition based on water-curable thermoplastic polymers and metal carboxylate silanol condensation catalysts UNION CARBIDE CORPORATION (US) 1987-11-17 US disclosed
EP-0212630-A2 Compositions based on water-curable thermoplastic polymers and metal carboxylate silanol condensation catalysts UNION CARBIDE CORPORATION (US) 1987-03-04 EP disclosed
US-4579913-A Composition of a relatively stable polymer of an olefinic monomer and an unsaturated silane, and an organo titanate UNION CARBIDE CORPORATION (US) 1986-04-01 US disclosed
US-4526930-A Contains organotitanate for ester exchange UNION CARBIDE CORPORATION (US) 1985-07-02 US disclosed
EP-0135923-A2 Production of water-curable, silane modified thermoplastic polymers UNION CARBIDE CORPORATION (US) 1985-04-03 EP disclosed