Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.37 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.35 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4568241 | 0.77 | PTPN5 (0.38) | L3MBTL1EPHX1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL18550749 | 0.72 | L3MBTL1 (0.43) | L3MBTL1EPHX1PTPN7DUSP3KIF11 | |
| SCHEMBL31394432 | 0.72 | L3MBTL1 (0.51) | L3MBTL1KIF11KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL18340946 | 0.72 | L3MBTL1 (0.51) | L3MBTL1KIF11KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL5437194 | 0.72 | KIF11 (0.54) | KIF11 | |
| SCHEMBL3660048 | 0.70 | L3MBTL1 (0.48) | L3MBTL1KIF11KMT2AMAPTGAA | |
| SCHEMBL2579126 | 0.70 | KIF11 (0.51) | EPHX1KIF11KMT2AMAPTGAA | |
| SCHEMBL31321380 | 0.70 | L3MBTL1 (0.41) | L3MBTL1KIF11KMT2AGAASMN1; SMN2 | |
| SCHEMBL23496839 | 0.69 | L3MBTL1 (0.56) | L3MBTL1KIF11KMT2AMAPTGAA | |
| SCHEMBL29876645 | 0.69 | L3MBTL1 (0.56) | L3MBTL1KIF11KMT2AMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007510-A1 | COMPOUNDS FOR BINDING AND IMAGING AMYLOID PLAQUES AND THEIR USE | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-01-19 | — | — | WO | disclosed |