Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 7/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | HTR1D | P28221 | 1/20 | 0.30 |
| ▸ | HTR1B | P28222 | 1/20 | 0.30 |
| ▸ | HTR1E | P28566 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | HTR5A | P47898 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18977430 | 0.70 | CHRM2 (0.55) | MPOSLC6A4ADRB2CHRM2HTR2A | |
| SCHEMBL3671544 | 0.66 | IDO1 (0.33) | — | |
| SCHEMBL30740916 | 0.66 | TAAR1 (0.56) | MPOSLC6A4CHRM2HTR2AHTR1A | |
| SCHEMBL3201894 | 0.64 | CHRM2 (0.41) | CHRM2 | |
| SCHEMBL8675623 | 0.63 | MPO (0.41) | MPOSLC6A4CHRM2HTR2A | |
| SCHEMBL27593083 | 0.63 | MPO (0.66) | MPOCHRM2 | |
| SCHEMBL4530303 | 0.62 | MPO (0.44) | MPOSLC6A4HTR2A | |
| SCHEMBL21137531 | 0.62 | CYP3A4 (0.42) | MPOSLC6A4CHRM2HTR2A | |
| SCHEMBL3441609 | 0.61 | SIGMAR1 (0.75) | — | |
| SCHEMBL12085586 | 0.61 | CHRM2 (0.60) | CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966223-B1 | CATALYST COMPOSITION COMPRISING GROUP 4 TRANSITION METAL COMPLEXES AND METHOD FOR PREPARING POLYOLEFINS USING THE SAME | LG CHEMICAL LTD (KR) | 2013-08-14 | — | — | EP | disclosed |
| US-7807762-B2 | Catalyst composition comprising Group 4 transition metal complexes and method for preparing polyolefins using the same | LG CHEM, LTD. (KR) | 2010-10-05 | — | — | US | disclosed |
| US-20090005525-A1 | Catalyst Composition Comprising Group 4 Transition Metal Complexes and Method for Preparing Polyolefins Using the Same | LG CHEM , LTD. (KR) | 2009-01-01 | — | — | US | disclosed |
| EP-1966223-A1 | CATALYST COMPOSITION COMPRISING GROUP 4 TRANSITION METAL COMPLEXES AND METHOD FOR PREPARING POLYOLEFINS USING THE SAME | LG Chem. Ltd. (KR) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007078133-A1 | CATALYST COMPOSITION COMPRISING GROUP 4 TRANSITION METAL COMPLEXES AND METHOD FOR PREPARING POLYOLEFINS USING THE SAME | LG CHEM. LTD. (KR) | 2007-07-12 | — | — | WO | disclosed |