⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3073644 | 0.74 | — | — | |
| SCHEMBL17844011 | 0.72 | — | — | |
| Hydroxyurea SCHEMBL4004 | 0.70 | — | — | |
| Hydroxyurea SCHEMBL5329855 | 0.70 | LMNA (1.00) | — | |
| Hydroxyurea SCHEMBL93814 | 0.70 | LMNA (1.00) | — | |
| SCHEMBL29408430 | 0.70 | — | — | |
| SCHEMBL29149672 | 0.70 | — | — | |
| Potassium SCHEMBL30716852 | 0.70 | — | — | |
| Urea SCHEMBL27373626 | 0.69 | LMNA (0.44) | — | |
| SCHEMBL439322 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109734729-B | Preparation method and application of hexanuclear amide compound | 潍坊科技学院 | 2021-03-12 | — | — | CN | claimed |
| US-7662856-B2 | Compositions having antimycrobial activity including a hydroxamate or a hydroxamate and a hydroxlyamine | THE UNIVERSITY OF HOUSTON SYSTEM (US) | 2010-02-16 | — | — | US | claimed |
| US-20080249181-A1 | Compositions Having Antimycrobial Activity Including a Hydroxamate or a Hydroxamate and a Hydroxlyamine | KOHN HAROLD | 2008-10-09 | — | — | US | claimed |
| US-20060084688-A1 | Aromatic sulfone hydroxamic acid metalloprotease inhibitor | BARTA THOMAS E | 2006-04-20 | — | — | US | claimed |
| WO-2005020973-A2 | COMPOSITIONS HAVING ANTIMYCROBIAL ACTIVITY INCLUDING A HYDROXAMATE OR A HYDROXAMATE AND A HYDROXYLAMINE | THE UNIVERSITY OF HOUSTON SYSTEM (US) | 2005-03-10 | — | — | WO | claimed |
| JP-1025788-A | — | — | None | — | — | JP | disclosed |
| CN-119118874-A | Novel impurity compound, method for producing the same, method for measuring content of the same, and use of the same | 科笛生物医药(无锡)有限公司 | 2024-12-13 | — | — | CN | disclosed |
| CN-117412753-A | Bruton's tyrosine kinase inhibitors and methods of use thereof | 詹森药业有限公司 | 2024-01-16 | — | — | CN | disclosed |
| CN-107304191-B | Indolylamine 2,3-dioxygenase inhibitor and preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-09-29 | — | — | CN | disclosed |
| EP-3181556-B1 | MICROMOLECULE COMPOUND, METHOD OF SYNTHESIS AND APPLICATION THEREOF | TECHNODERMA MEDICINES PTE LTD (CN) | 2021-09-29 | — | — | EP | disclosed |
| US-9920022-B2 | Small molecule compound and synthesizing method and uses thereof | TECHNODERMA MEDICINES PTE LTD. (CN) | 2018-03-20 | — | — | US | disclosed |
| EP-3181556-A1 | MICROMOLECULE COMPOUND, METHOD OF SYNTHESIS AND APPLICATION THEREOF | Technoderma Medicines Pte Ltd (CN) | 2017-06-21 | — | — | EP | disclosed |
| WO-1998009961-A1 | INDAZOLE DERIVATIVES AND THEIR USE AS INHIBITORS OF PHOSPHODIESTERASE (PDE) TYPE IV AND THE PRODUCTION OF TUMOR NECROSIS FACTOR (TNF) | PFIZER INC. (US) | 1998-03-12 | — | — | WO | disclosed |
| EP-0538384-A4 | OXAMIDES | SMITHKLINE BEECHAM CORP (US) | 1995-04-12 | — | — | EP | disclosed |
| US-5393788-A | Phenylalkyl oxamides | SMITHKLINE BEECHAM CORPORATION (US) | 1995-02-28 | — | — | US | disclosed |
| EP-0538384-A1 | OXAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 1993-04-28 | — | — | EP | disclosed |
| CN-1060652-A | OXAMIDES | SMITHKLINE BEECHAM CORP (US) | 1992-04-29 | — | — | CN | disclosed |
| WO-1992000968-A1 | OXAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 1992-01-23 | — | — | WO | disclosed |
| JP-S6425788-A | SILANE COMPOUND HAVING MODIFYING ACTION OF INORGANIC CARRIER SURFACE, ITS PRODUCTION AND USE THEREOF | HARA SHOJI | 1989-01-27 | — | — | JP | disclosed |
| US-4029671-A | ANTIBACTERIAL, ANTIPROTOZOAL, ANTIFUNGAL | ELI LILLY AND COMPANY (US) | 1977-06-14 | — | — | US | disclosed |