Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.71 |
| ▸ | RAB9A | P51151 | 2/20 | 0.71 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.63 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.63 |
| ▸ | GRM5 | P41594 | 4/20 | 0.60 |
| ▸ | PGR | P06401 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.58 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.58 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.58 |
| ▸ | KCNQ1 | P51787 | 2/20 | 0.58 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.58 |
| ▸ | AR | P10275 | 1/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.57 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3667947 | 0.93 | PGR (0.64) | NPC1RAB9AKCNK3KCNK9GRM5 | |
| SCHEMBL13192836 | 0.91 | NPC1 (0.70) | NPC1RAB9AKCNK3KCNK9GRM5 | |
| SCHEMBL18745409 | 0.89 | NPC1 (0.67) | NPC1RAB9AKCNK3KCNK9GRM5 | |
| SCHEMBL27874895 | 0.88 | NPC1 (0.73) | NPC1RAB9AKCNK3KCNK9MAPT | |
| SCHEMBL3673613 | 0.88 | KMT2A (0.64) | NPC1RAB9AKCNK3PGRTP53 | |
| SCHEMBL1486169 | 0.85 | GRM5 (0.82) | NPC1RAB9AKCNK3KCNK9GRM5 | |
| SCHEMBL16507657 | 0.84 | NPC1 (0.61) | NPC1RAB9AKCNK3KCNK9GRM5 | |
| SCHEMBL3680125 | 0.84 | BRAF (0.61) | NPC1RAB9AGRM5PGRTP53 | |
| SCHEMBL3669695 | 0.84 | PGR (0.60) | NPC1RAB9APGRNR1H4AR | |
| SCHEMBL12412616 | 0.84 | GRM5 (0.85) | NPC1RAB9AGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329444-B1 | Halogenated aromatic compound, (co)polymer thereof, and proton-conductive membrane comprising same | JSR CORP (JP) | 2010-05-05 | — | — | EP | disclosed |
| US-6933068-B2 | Polymer electrolyte membrane and solid polymer electrolyte fuel cell using same | HONDA GIKEN KOGYO KABUSHIKI KAISHA (JP) | 2005-08-23 | — | — | US | disclosed |
| US-6833426-B2 | A proton-conductive membrane containing the sulfonic acid group-containing polyarylene (co)polymer | JSR CORPORATION (JP) | 2004-12-21 | — | — | US | disclosed |
| US-20030173547-A1 | Halogenated aromatic compound, (co)polymer thereof, and proton-conductive membrane comprising same | JSR CORPORATION (JP) | 2003-09-18 | — | — | US | disclosed |
| EP-1329444-A1 | Halogenated aromatic compound, (co)polymer thereof, and proton-conductive membrane comprising same | JSR Corporation (JP) | 2003-07-23 | — | — | EP | disclosed |
| US-20020172850-A1 | Polymer electrolyte membrane and solid polymer electrolyte fuel cell using same | HONDA GIKEN KOGYO KABUSHIKI KAISHA, JSR CORPORATION | 2002-11-21 | — | — | US | disclosed |