Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 14/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26554655 | 0.86 | SIGMAR1 (0.44) | HRH3KCNH2CYP2D6SIGMAR1 | |
| SCHEMBL25530321 | 0.85 | HRH3 (0.49) | HRH3KCNH2CYP2D6MEN1KMT2A | |
| SCHEMBL10130722 | 0.83 | MEN1 (0.54) | HRH3KCNH2CYP2D6MEN1KMT2A | |
| SCHEMBL13999393 | 0.83 | HRH3 (0.53) | HRH3KCNH2CYP2D6MEN1KMT2A | |
| SCHEMBL25533360 | 0.82 | HRH3 (0.45) | HRH3KCNH2CYP2D6MEN1KMT2A | |
| SCHEMBL22249046 | 0.82 | HRH3 (0.45) | HRH3KCNH2CYP2D6MEN1KMT2A | |
| SCHEMBL25533363 | 0.82 | HRH3 (0.45) | HRH3KCNH2CYP2D6MEN1KMT2A | |
| SCHEMBL25443823 | 0.80 | HRH3 (0.51) | HRH3KCNH2CYP2D6MEN1KMT2A | |
| SCHEMBL2747052 | 0.80 | CHRNB2 (0.37) | MEN1KMT2ADPP4 | |
| SCHEMBL20315414 | 0.80 | HRH3 (0.50) | HRH3KCNH2CYP2D6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1813611-B1 | 1-SUBSTITUTED-3- BETA-D-GLYCOPYRANOSYLATED NITROGENOUS HETERO- CYCLIC COMPOUNDS AND MEDICINES CONTAINING THE SAME | KISSEI PHARMACEUTICAL (JP) | 2014-10-01 | — | — | EP | disclosed |
| US-7750145-B2 | 1-substituted-3-β-D-glucopyranosylated nitrogenous hetero-cyclic compounds and medicines containing the same | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2010-07-06 | — | — | US | disclosed |
| US-20100144751-A1 | IMIDAZO[1,2-a]PYRIDINE COMPOUNDS AS RECEPTOR TYROSINE KINASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2010-06-10 | — | — | US | disclosed |
| EP-2175934-A2 | COSMETIC MEDIUM BASED ON VINYLIMIDAZOLE POLYMERS | BASF SE (DE) | 2010-04-21 | — | — | EP | disclosed |
| US-20090074738-A1 | 1-SUBSTITUTED-3-BETA-D-GLUCOPYRANOSYLATED NITROGENOUS HETERO-CYCLIC COMPOUNDS AND MEDICINES CONTAINING THE SAME | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-03-19 | — | — | US | disclosed |
| WO-2009007339-A2 | COSMETIC MEDIUM BASED ON VINYLIMIDAZOLE POLYMERS | BASF SE (DE) | 2009-01-15 | — | — | WO | disclosed |
| EP-1813611-A1 | 1-SUBSTITUTED-3- BETA-D-GLUCOPYRANOSYLATED NITROGENOUS HETERO- CYCLIC COMPOUNDS AND MEDICINES CONTAINING THE SAME | Kissei Pharmaceutical Co., Ltd. (JP) | 2007-08-01 | — | — | EP | disclosed |
| EP-1455739-A1 | COSMETIC AGENT CONTAINING AT LEAST ONE COPOLYMER HAVING N-VINYLLACTAM UNITS | BASF AKTIENGESELLSCHAFT (DE) | 2004-09-15 | — | — | EP | disclosed |
| WO-2003053381-A1 | COSMETIC AGENT CONTAINING AT LEAST ONE COPOLYMER HAVING N-VINYLLACTAM UNITS | BASF AKTIENGESELLSCHAFT (DE) | 2003-07-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144751-A1 | IMIDAZO[1,2-a]PYRIDINE COMPOUNDS AS RECEPTOR TYROSINE KINASE INHIBITORS | PIM1, PIM3, PIM2 | HRH3 1924/4885KCNH2 1427/4885CYP2D6 574/4885 |
| US-20090074738-A1 | 1-SUBSTITUTED-3-BETA-D-GLUCOPYRANOSYLATED NITROGENOUS HETERO-CYCLIC COMPOUNDS AND MEDICINES CONTAINING THE SAME | SLC5A1, SLC5A2, UGGT1 | HRH3 3873/4885KCNH2 913/4885CYP2D6 195/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.