SCHEMBL3679206

SCHEMBL3679206

CC(Br)C(=O)OCC(OC(=O)C(C)Br)C(COC(=O)C(C)Br)OC(=O)C(C)Br

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.36
TSHR P16473 2/20 0.30
FAAH O00519 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3682466 0.90 TDP1 (0.41) TDP1
SCHEMBL3681384 0.90 TDP1 (0.46) TDP1
SCHEMBL3683342 0.82 ALDH1A1 (0.36)
SCHEMBL4413628 0.78 TSHR (0.48) TDP1TSHR
SCHEMBL10030163 0.73 MAPT (0.46) TDP1TSHRFAAH
SCHEMBL3680973 0.73 TDP1 (0.36) TDP1TSHR
SCHEMBL435015 0.72 TSHR (0.35) TSHRFAAH
SCHEMBL21811604 0.72 ZDHHC7 (0.31) TSHRFAAH
SCHEMBL10471153 0.72
SCHEMBL435016 0.72 TSHR (0.33) TSHRFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2013240-B1 PROCESS FOR THE PREPARATION OF CROSSLINKED NITROXIDE POLYMERS PIOTREK CO LTD (JP) 2017-05-31 EP disclosed
US-8492511-B2 Process for the preparation of crosslinked nitroxide polymers PIOTREK CO., LTD. (JP) 2013-07-23 US disclosed
US-20100240858-A1 PROCESS FOR THE PREPARATION OF CROSSLINKED NITROXIDE POLYMERS PIOTREK CO., LTD. (JP) 2010-09-23 US disclosed
EP-2013240-A1 PROCESS FOR THE PREPARATION OF CROSSLINKED NITROXIDE POLYMERS PIOTREK CO., LTD. (JP) 2009-01-14 EP disclosed
WO-2007115939-A1 PROCESS FOR THE PREPARATION OF CROSSLINKED NITROXIDE POLYMERS PIOTREK CO., LTD. (JP) 2007-10-18 WO disclosed