SCHEMBL3679531

SCHEMBL3679531

C=CCCCc1cccc(C=C)c1

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.42
TP53 P04637 1/20 0.42
HDAC1 Q13547 2/20 0.41
HDAC4 P56524 2/20 0.41
ALDH1A1 P00352 2/20 0.37
TSHR P16473 1/20 0.37
TLR8 Q9NR97 1/20 0.36
OPRM1 P35372 3/20 0.36
OPRD1 P41143 3/20 0.36
OPRK1 P41145 3/20 0.36
USP2 O75604 1/20 0.35
HPGD P15428 1/20 0.35
FAAH O00519 1/20 0.35
MEF2D Q14814 1/20 0.33
AKR1B10 O60218 1/20 0.33
AKR1B1 P15121 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3674435 0.89 TP53 (0.45) TDP1TP53HDAC1ALDH1A1TSHR
SCHEMBL595251 0.86 TP53 (0.47) TDP1TP53ALDH1A1TSHROPRM1
SCHEMBL595016 0.84 TP53 (0.52) TDP1TP53ALDH1A1TSHROPRM1
SCHEMBL29375309 0.84 TP53 (0.52) TDP1TP53ALDH1A1TSHROPRM1
SCHEMBL700528 0.83 TP53 (0.44) TDP1TP53HDAC4ALDH1A1TSHR
SCHEMBL29619562 0.82 TP53 (0.50) TDP1TP53ALDH1A1TSHROPRM1
SCHEMBL1645656 0.82 TP53 (0.50) TDP1TP53ALDH1A1TSHROPRM1
SCHEMBL23648072 0.81 CYP4F2 (0.43) TDP1TP53ALDH1A1TSHROPRM1
SCHEMBL23648092 0.81 TP53 (0.42) TDP1TP53HDAC4ALDH1A1TSHR
SCHEMBL30540423 0.81 TP53 (0.47) TDP1TP53HDAC4HPGDMEF2D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5418276-A Styrene copolymer, syndiotactic, heat resistance, chemical resistance IDEMITSU KOSAN CO., LTD. (JP) 1995-05-23 US claimed
US-5362814-A Styrene polymers with olefin monomers and diolefin monomers for impact strength in molding materials IDEMITSU KOSAN CO., LTD. (JP) 1994-11-08 US claimed
US-8461271-B2 Graft copolymer, thermoplastic resin composition comprising the graft copolymer, and those production method IDEMITSU KOSAN CO., LTD. (JP) 2013-06-11 US disclosed
EP-1408080-B1 POLYOLEFIN RESIN COMPOSITION IDEMITSU KOSAN CO (JP) 2012-12-26 EP disclosed
US-20100076146-A1 GRAFT COPOLYMER, THERMOPLASTIC RESIN COMPOSITION COMPRISING THE GRAFT COPOLYMER, AND THOSE PRODUCTION METHOD IDEMITSU KOSAN CO., LTD. (JP) 2010-03-25 US disclosed
US-7531605-B2 Process for producing polyolefin resin composition and polypropylene composition IDEMITSU KOSAN CO., LTD. (JP) 2009-05-12 US disclosed
EP-1375538-B1 PROCESS FOR PRODUCING POLYOLEFIN RESIN COMPOSITION AND POLYPROPYLENE COMPOSITION IDEMITSU KOSAN CO (JP) 2008-01-09 EP disclosed
US-7193013-B2 Polyolefin resin composition IDEMITSU KOSAN CO. LTD. (JP) 2007-03-20 US disclosed
US-7189788-B2 Polyolefin resin composition IDEMITSU KOSAN CO. LTD. (JP) 2007-03-13 US disclosed
EP-1367093-B1 POLYOLEFIN RESIN COMPOSITION IDEMITSU KOSAN CO (JP) 2005-12-14 EP disclosed
US-20040176520-A1 Polyolefin resin composition IDEMITSU KOSAN CO. LTD. (JP) 2004-09-09 US disclosed
EP-1375538-A1 PROCESS FOR PRODUCING POLYOLEFIN RESIN COMPOSITION AND POLYPROPYLENE COMPOSITION IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2004-01-02 EP disclosed
EP-1367093-A1 POLYOLEFIN RESIN COMPOSITION IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2003-12-03 EP disclosed
EP-0686649-B1 PROPYLENE BLOCK COPOLYMER, PROCESS FOR PRODUCING THE SAME, AND MODIFIED COPOLYMER PRODUCED THEREFROM IDEMITSU KOSAN CO (JP) 2000-08-02 EP disclosed
US-5670580-A POLYMERS FOR ANTISTATIC AGENTS, ADHESIVES AND FIREPROOFING IDEMITSU KOSAN CO., LTD. (JP) 1997-09-23 US disclosed
EP-0559108-B1 Graft copolymer, process for production thereof and resin composition containing same IDEMITSU KOSAN CO (JP) 1997-05-28 EP disclosed
EP-0686649-A1 PROPYLENE BLOCK COPOLYMER, PROCESS FOR PRODUCING THE SAME, AND MODIFIED COPOLYMER PRODUCED THEREFROM IDEMITSU KOSAN COMPANY LIMITED (JP) 1995-12-13 EP disclosed
US-5418276-A Styrene copolymer, syndiotactic, heat resistance, chemical resistance IDEMITSU KOSAN CO., LTD. (JP) 1995-05-23 US disclosed
US-5362814-A Styrene polymers with olefin monomers and diolefin monomers for impact strength in molding materials IDEMITSU KOSAN CO., LTD. (JP) 1994-11-08 US disclosed
EP-0559108-A1 Graft copolymer, process for production thereof and resin composition containing same IDEMITSU KOSAN COMPANY LIMITED (JP) 1993-09-08 EP disclosed