SCHEMBL3674435

SCHEMBL3674435

C=CCCc1cccc(C=C)c1

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
ALDH1A1 P00352 2/20 0.39
TSHR P16473 1/20 0.39
OPRM1 P35372 4/20 0.38
OPRD1 P41143 4/20 0.38
OPRK1 P41145 4/20 0.38
FAAH O00519 1/20 0.36
CYP4F2 P78329 1/20 0.33
CYP4A11 Q02928 1/20 0.33
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
POLB P06746 1/20 0.32
MAOA P21397 2/20 0.31
MAOB P27338 2/20 0.31
PLAU P00749 1/20 0.31
HDAC1 Q13547 1/20 0.31
PTGS2 P35354 1/20 0.31
TAAR1 Q96RJ0 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3679531 0.89 TDP1 (0.42) TP53TDP1ALDH1A1TSHROPRM1
SCHEMBL595016 0.87 TP53 (0.52) TP53TDP1ALDH1A1TSHROPRM1
SCHEMBL29375309 0.87 TP53 (0.52) TP53TDP1ALDH1A1TSHROPRM1
SCHEMBL1645656 0.85 TP53 (0.50) TP53TDP1ALDH1A1TSHROPRM1
SCHEMBL29619562 0.85 TP53 (0.50) TP53TDP1ALDH1A1TSHROPRM1
SCHEMBL17006079 0.85 MAOA (0.44) TDP1ALDH1A1OPRM1OPRD1OPRK1
SCHEMBL20008279 0.85 TP53 (0.42) TP53TDP1ALDH1A1TSHROPRM1
SCHEMBL29619625 0.83 TP53 (0.48) TP53TDP1ALDH1A1TSHROPRM1
SCHEMBL1646925 0.83 TP53 (0.48) TP53TDP1ALDH1A1TSHROPRM1
SCHEMBL595251 0.82 TP53 (0.47) TP53TDP1ALDH1A1TSHROPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5418276-A Styrene copolymer, syndiotactic, heat resistance, chemical resistance IDEMITSU KOSAN CO., LTD. (JP) 1995-05-23 US claimed
US-5362814-A Styrene polymers with olefin monomers and diolefin monomers for impact strength in molding materials IDEMITSU KOSAN CO., LTD. (JP) 1994-11-08 US claimed
US-8461271-B2 Graft copolymer, thermoplastic resin composition comprising the graft copolymer, and those production method IDEMITSU KOSAN CO., LTD. (JP) 2013-06-11 US disclosed
EP-1408080-B1 POLYOLEFIN RESIN COMPOSITION IDEMITSU KOSAN CO (JP) 2012-12-26 EP disclosed
US-20100076146-A1 GRAFT COPOLYMER, THERMOPLASTIC RESIN COMPOSITION COMPRISING THE GRAFT COPOLYMER, AND THOSE PRODUCTION METHOD IDEMITSU KOSAN CO., LTD. (JP) 2010-03-25 US disclosed
US-7531605-B2 Process for producing polyolefin resin composition and polypropylene composition IDEMITSU KOSAN CO., LTD. (JP) 2009-05-12 US disclosed
EP-1375538-B1 PROCESS FOR PRODUCING POLYOLEFIN RESIN COMPOSITION AND POLYPROPYLENE COMPOSITION IDEMITSU KOSAN CO (JP) 2008-01-09 EP disclosed
US-7193013-B2 Polyolefin resin composition IDEMITSU KOSAN CO. LTD. (JP) 2007-03-20 US disclosed
US-7189788-B2 Polyolefin resin composition IDEMITSU KOSAN CO. LTD. (JP) 2007-03-13 US disclosed
EP-1367093-B1 POLYOLEFIN RESIN COMPOSITION IDEMITSU KOSAN CO (JP) 2005-12-14 EP disclosed
US-20040176520-A1 Polyolefin resin composition IDEMITSU KOSAN CO. LTD. (JP) 2004-09-09 US disclosed
EP-0737694-A1 PROCESS FOR PRODUCING OLEFIN POLYMER AND ETHYLENE POLYMER IDEMITSU KOSAN COMPANY LIMITED (JP) 1996-10-16 EP disclosed
EP-0686649-A1 PROPYLENE BLOCK COPOLYMER, PROCESS FOR PRODUCING THE SAME, AND MODIFIED COPOLYMER PRODUCED THEREFROM IDEMITSU KOSAN COMPANY LIMITED (JP) 1995-12-13 EP disclosed
EP-0667359-A1 OLEFIN COPOLYMERS AND PROCESS FOR PRODUCING THE SAME IDEMITSU KOSAN COMPANY LIMITED (JP) 1995-08-16 EP disclosed
US-5418276-A Styrene copolymer, syndiotactic, heat resistance, chemical resistance IDEMITSU KOSAN CO., LTD. (JP) 1995-05-23 US disclosed
US-5362814-A Styrene polymers with olefin monomers and diolefin monomers for impact strength in molding materials IDEMITSU KOSAN CO., LTD. (JP) 1994-11-08 US disclosed
EP-0559108-A1 Graft copolymer, process for production thereof and resin composition containing same IDEMITSU KOSAN COMPANY LIMITED (JP) 1993-09-08 EP disclosed
US-4127564-A DIOLEFIN-PHENOLIC COPOLYMER DYNAPOL (US) 1978-11-28 US disclosed
US-3996198-A One step preparation of linear antioxidant phenolic polymers involving use of impure diolefin feedstock and aluminum catalyst under ortho alkylation conditions DYNAPOL (US) 1976-12-07 US disclosed
US-3996160-A ANTIOXIDANT FROM A HYDROQUINONE AND A DIENE DYNAPOL CORPORATION (US) 1976-12-07 US disclosed