Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 9/20 | 0.42 |
| ▸ | HTR2A | P28223 | 9/20 | 0.42 |
| ▸ | DRD3 | P35462 | 9/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3678732 | 0.96 | HTR2C (0.52) | HTR2CHRH4DRD2HTR2ADRD3 | |
| SCHEMBL3685191 | 0.96 | HTR2C (0.52) | HTR2CHRH4DRD2HTR2ADRD3 | |
| SCHEMBL3680126 | 0.80 | HRH3 (0.45) | HRH4HRH3HRH1 | |
| SCHEMBL3682748 | 0.79 | HTR2C (0.50) | HTR2CDRD2HTR2ADRD3 | |
| SCHEMBL15971536 | 0.78 | HTR2C (0.73) | HTR2CDRD2HTR2ADRD3CNR2 | |
| SCHEMBL3683432 | 0.77 | HRH4 (0.52) | HRH4HRH3HRH1 | |
| SCHEMBL3686270 | 0.77 | HTR2C (0.52) | HTR2CHRH3DRD2HTR2ADRD3 | |
| SCHEMBL15971496 | 0.76 | HTR2C (0.71) | HTR2CDRD2HTR2ADRD3CNR2 | |
| SCHEMBL3683639 | 0.76 | HRH4 (0.47) | HRH4HRH3 | |
| SCHEMBL3685093 | 0.76 | HRH4 (0.47) | HRH4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7799775-B2 | such as 3-amino-5,6-dimethyl-2-[3-(4-quinolin-2-ylpiperazin-1-yl)propylthio]-3H-thieno[2,3-d]pyrimidin-4-one, having serotonin receptor modulatory activity, used for treating irritable bowel syndrome | ASKA PHARMACEUTICAL CO., LTD. (JP) | 2010-09-21 | — | — | US | claimed |
| EP-1724267-B1 | PYRIMIDINE DERIVATIVE | ASKA PHARM CO LTD (JP) | 2013-11-06 | — | — | EP | disclosed |
| EP-1724267-B1 | PYRIMIDINE DERIVATIVE | ASKA PHARM CO LTD (JP) | 2013-11-06 | — | — | EP | disclosed |
| US-7807735-B2 | mixing lignocellulosic material with a phenolic resin binder, adding to the mixture an emulsion of nonsaponified and saponified wax, an alkyl phenol component containing C20-C42 alkyl group; a polynaphthalenesulfonic salt as dispersant/surfactant and water; solidification; dimensionally stable | HEXION SPECIALTY CHEMICALS, INC. (US) | 2010-10-05 | — | — | US | disclosed |
| US-7799775-B2 | such as 3-amino-5,6-dimethyl-2-[3-(4-quinolin-2-ylpiperazin-1-yl)propylthio]-3H-thieno[2,3-d]pyrimidin-4-one, having serotonin receptor modulatory activity, used for treating irritable bowel syndrome | ASKA PHARMACEUTICAL CO., LTD. (JP) | 2010-09-21 | — | — | US | disclosed |
| US-7799775-B2 | such as 3-amino-5,6-dimethyl-2-[3-(4-quinolin-2-ylpiperazin-1-yl)propylthio]-3H-thieno[2,3-d]pyrimidin-4-one, having serotonin receptor modulatory activity, used for treating irritable bowel syndrome | ASKA PHARMACEUTICAL CO., LTD. (JP) | 2010-09-21 | — | — | US | disclosed |
| US-7799775-B2 | such as 3-amino-5,6-dimethyl-2-[3-(4-quinolin-2-ylpiperazin-1-yl)propylthio]-3H-thieno[2,3-d]pyrimidin-4-one, having serotonin receptor modulatory activity, used for treating irritable bowel syndrome | ASKA PHARMACEUTICAL CO., LTD. (JP) | 2010-09-21 | — | — | US | disclosed |
| US-20090272292-A1 | mixing lignocellulosic material with a phenolic resin binder, adding to the mixture an emulsion of nonsaponified and saponified wax, an alkyl phenol component containing C20-C42 alkyl group; a polynaphthalenesulfonic salt as dispersant/surfactant and water; solidification; dimensionally stable | HEXION SPECIALTY CHEMICALS, INC. | 2009-11-05 | — | — | US | disclosed |
| US-7563826-B2 | Wax component comprising nonsaponifiable wax and saponified wax, alkyl phenol, dispersant/surfactant, carboxymethylcellulose component, and water; water resistance | HEXION SPECIALTY CHEMICALS, INC. (US) | 2009-07-21 | — | — | US | disclosed |
| US-7294189-B2 | Wax emulsion preservative compositions and method of manufacture | HEXION SPECIALTY CHEMICALS, INC. (US) | 2007-11-13 | — | — | US | disclosed |
| US-20060071196-A1 | Method of wood treatment and solution provided therefore | ECOTREAT, INC. | 2006-04-06 | — | — | US | disclosed |
| EP-1599547-A4 | EMULSIONS FOR LIGNOCELLULOSIC PRODUCTS, METHODS OF THEIR MANUFACTURE, IMPROVED LIGNOCELLULOSIC PRODUCTS AND METHODS FOR THEIR MANUFACTURE | HEXION SPECIALTY CHEMICALS INC (US) | 2006-01-18 | — | — | EP | disclosed |
| US-20060009535-A1 | Wax emulsion preservative compositions and method of manufacture | HEXION INC. (FORMERLY KNOWN AS MOMENTIVE SPECIALTY CHEMICALS INC.) | 2006-01-12 | — | — | US | disclosed |
| EP-1599547-A2 | EMULSIONS FOR LIGNOCELLULOSIC PRODUCTS, METHODS OF THEIR MANUFACTURE, IMPROVED LIGNOCELLULOSIC PRODUCTS AND METHODS FOR THEIR MANUFACTURE | Hexion Specialty Chemicals, Inc. (US) | 2005-11-30 | — | — | EP | disclosed |
| EP-1273403-B1 | Preservation of wood products | ROHM & HAAS (US) | 2005-08-31 | — | — | EP | disclosed |
| WO-2005039841-A2 | EMULSIONS FOR LIGNOCELLULOSIC PRODUCTS, METHODS OF THEIR MANUFACTURE, IMPROVED LIGNOCELLULOSIC PRODUCTS AND METHODS FOR THEIR MANUFACTURE | BORDEN CHEMICAL, INC. (US) | 2005-05-06 | — | — | WO | disclosed |
| US-6753016-B2 | CONTACTING WOOD MATERIAL WITH AN AQUEOUS TREATMENT SOLUTION COMPRISING AN IRON SALT AND AN OXIDANT TO PROVIDE IMPREGNATED WOOD MATERIAL; AND SEPARATING THE IMPREGNATED WOOD MATERIAL FROM THE AQUEOUS TREATMENT SOLUTION | ROHM AND HAAS COMPANY | 2004-06-22 | — | — | US | disclosed |
| US-20030086979-A1 | Preservation of wood products | ROHM AND HAAS COMPANY | 2003-05-08 | — | — | US | disclosed |
| EP-1273403-A1 | Preservation of wood products | ROHM AND HAAS COMPANY (US) | 2003-01-08 | — | — | EP | disclosed |
| EP-0922386-A2 | Controlled release compositions | ROHM AND HAAS COMPANY (US) | 1999-06-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030086979-A1 | Preservation of wood products | SOD1, SOD3, AOC1 | HTR2C 4045/4885HRH4 994/4885HRH3 853/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.