Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 2/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP2 | P42575 | 1/20 | 0.33 |
| ▸ | CASP4 | P49662 | 1/20 | 0.33 |
| ▸ | CASP5 | P51878 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.31 |
| ▸ | ITGAV | P06756 | 2/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.30 |
| ▸ | TMPRSS15 | P98073 | 2/20 | 0.30 |
| ▸ | FOLR2 | P14207 | 1/20 | 0.30 |
| ▸ | FOLR1 | P15328 | 1/20 | 0.30 |
| ▸ | CRAT | P43155 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3679711 | 1.00 | CASP3 (0.33) | CASP3CASP1CASP2CASP4CASP5 | |
| SCHEMBL13410017 | 0.93 | CASP3 (0.34) | CASP3CASP1CASP2CASP4CASP5 | |
| Trifluoroacetic Acid SCHEMBL3683180 | 0.85 | S1PR1 (0.41) | CASP3 | |
| SCHEMBL3679709 | 0.85 | HPGD (0.30) | — | |
| Trifluoroacetic Acid SCHEMBL3683187 | 0.85 | S1PR1 (0.41) | CASP3 | |
| Trifluoroacetic Acid SCHEMBL3688859 | 0.84 | POLB (0.32) | CASP3CRAT | |
| Trifluoroacetic Acid SCHEMBL3688864 | 0.84 | POLB (0.32) | CASP3CRAT | |
| SCHEMBL14822937 | 0.82 | TAS1R3 (0.38) | CASP3CASP1CASP2CASP4CASP5 | |
| SCHEMBL13444028 | 0.81 | CASP3 (0.43) | CASP3CASP1CASP2CASP4CASP5 | |
| Trifluoroacetic Acid SCHEMBL3679966 | 0.80 | ALDH1A1 (0.36) | HDAC4HDAC6HDAC3HDAC1CRAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008109991-A1 | INHIBITORS OF CARNITINE PALMITOYLTRANSFERASE AND TREATING CANCER | UNIVERSITY HEALTH NETWORK (CA) | 2008-09-18 | — | — | WO | claimed |
| US-8410150-B2 | Inhibitors of carnitine palmitoyltransferase and treating cancer | UNIVERSITY HEALTH NETWORK (CA) | 2013-04-02 | — | — | US | disclosed |
| US-20100105900-A1 | INHIBITORS OF CARNITINE PALMITOYLTRANSFERASE AND TREATING CANCER | UNIVERSITY HEALTH NETWORK | 2010-04-29 | — | — | US | disclosed |
| WO-2008109991-A1 | INHIBITORS OF CARNITINE PALMITOYLTRANSFERASE AND TREATING CANCER | UNIVERSITY HEALTH NETWORK (CA) | 2008-09-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100105900-A1 | INHIBITORS OF CARNITINE PALMITOYLTRANSFERASE AND TREATING CANCER | CPT1A, CPT1B, CPT2 | CASP3 2249/4885CASP1 2533/4885CASP2 2900/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.