Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3119117 | 0.92 | MAPT (0.30) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL3119852 | 0.89 | — | — | |
| Hydrochloric Acid SCHEMBL5951783 | 0.85 | HTR7 (0.35) | ALDH1A1NISCH | |
| Hydrochloric Acid SCHEMBL6895703 | 0.84 | HTR1A (0.39) | ALDH1A1HPGDHSD17B10NISCH | |
| Fluoride Ion SCHEMBL7640470 | 0.83 | HTR7 (0.35) | ALDH1A1HPGDMAPK1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL6886266 | 0.81 | HTR7 (0.34) | ALDH1A1NISCH | |
| Hydrochloric Acid SCHEMBL7192493 | 0.80 | USP30 (0.32) | — | |
| Hydrochloric Acid SCHEMBL6885461 | 0.80 | HTR1A (0.37) | NISCH | |
| Hydrochloric Acid SCHEMBL1028615 | 0.79 | NISCH (0.32) | ALDH1A1HPGDHSD17B10NISCH | |
| Hydrochloric Acid SCHEMBL5951629 | 0.77 | GSTP1 (0.36) | NISCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1241194-B1 | POLYMER AND PROCESS FOR PRODUCING THE SAME | MITSUI CHEMICALS INC (JP) | 2013-09-04 | — | — | EP | disclosed |
| US-7714087-B2 | Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof | MITSUI CHEMICALS, INC. (JP) | 2010-05-11 | — | — | US | disclosed |
| US-20090137757-A1 | Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof | IMUTA JUNICHI | 2009-05-28 | — | — | US | disclosed |
| US-7393907-B2 | Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof | MITSUI CHEMICALS, INC. (JP) | 2008-07-01 | — | — | US | disclosed |
| US-6995229-B2 | Polymer and process for producing the same | MITSUI CHEMICALS, INC. (JP) | 2006-02-07 | — | — | US | disclosed |
| US-20040122192-A1 | Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof | MITSUI CHEMICALS, INC. | 2004-06-24 | — | — | US | disclosed |
| US-6753378-B2 | GRAFTED WITH CARBOXYL- OR ANHYDRIDE CONTAINING COMPOUND; MELT PROCESSABILITY, CHEMICAL RESISTANCE, ELECTRICAL AND MECHANICAL PROPERTIES; INJECTION AND BLOW MOLDING; FILMS, SHEETS | MITSUI CHEMICALS, INC. (JP) | 2004-06-22 | — | — | US | disclosed |
| US-20030120003-A1 | Polymer and process for producing the same | MITSUI CHEMICALS, INC. (JP) | 2003-06-26 | — | — | US | disclosed |
| US-6583237-B1 | Silyl-terminated olefin polymers; catalyst is transition metal cyclopentadiene compound, organoaluminum oxycompound, compounds that form an ion pair, organoaluminum compound, organosilicon compound, a dialkylzinc compound, and hydrogen | MITSUI CHEMICALS, INC. (JP) | 2003-06-24 | — | — | US | disclosed |
| US-20030023002-A1 | Branched polyolefin, process for producing the same, and thremoplastic resin composition containing branched polyolefin | MITSUI CHEMICALS, INC. (JP) | 2003-01-30 | — | — | US | disclosed |
| US-20020156207-A1 | Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof | MITSUI CHEMICALS, INC. (JP) | 2002-10-24 | — | — | US | disclosed |
| EP-1241194-A1 | POLYMER AND PROCESS FOR PRODUCING THE SAME | Mitsui Chemicals, Inc. (JP) | 2002-09-18 | — | — | EP | disclosed |
| EP-1186619-A2 | Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition contaning the copolymer, and uses thereof | Mitsui Chemicals, Inc. (JP) | 2002-03-13 | — | — | EP | disclosed |
| US-6297333-B1 | METALLOCENE TRANSITION METAL COMPOUND HAVING AN INDENYL GROUP AND A FLUORENYL GROUP AS LIGANDS, SPECIFIC SUBSTITUENT ON A SPECIFIC POSITION OF THE INDENYL GROUP GIVES HIGH MOLECULAR WEIGHT AND HIGH ACTIVITY | MITSUI CHEMICALS INC (JP) | 2001-10-02 | — | — | US | disclosed |
| US-6133490-A | WAX OF COPOLYMER OF ETHYLENE WITH AN AROMATIC VINYL COMPOUND. | MITSUI CHEMICALS INC. (JP) | 2000-10-17 | — | — | US | disclosed |
| US-6004897-A | TRANSITION METAL INDENE-FLUORINE COMPLEX COORDINATION CATALYST WITH ORGANOALUMINUM AND ALUMOXANE COMPOUNDS | MITSUI CHEMICALS, INC. (JP) | 1999-12-21 | — | — | US | disclosed |