Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 13/20 | 1.00 |
| ▸ | AKR1B10 | O60218 | 3/20 | 1.00 |
| ▸ | AKR1B1 | P15121 | 3/20 | 1.00 |
| ▸ | MMP2 | P08253 | 2/20 | 0.71 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.71 |
| ▸ | AKR1C2 | P52895 | 11/20 | 0.67 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.67 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.65 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.65 |
| ▸ | MGAM | O43451 | 1/20 | 0.61 |
| ▸ | MAOA | P21397 | 1/20 | 0.61 |
| ▸ | MAOB | P27338 | 1/20 | 0.61 |
| ▸ | XDH | P47989 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Drupanin SCHEMBL5144749 | 1.00 | AKR1C3 (1.00) | AKR1C3AKR1B10AKR1B1MMP2PAK1 | |
| Drupanin SCHEMBL20472013 | 0.93 | AKR1C3 (0.87) | AKR1C3AKR1B10AKR1B1MMP2PAK1 | |
| Plicatin B SCHEMBL1227605 | 0.85 | AKR1C3 (0.73) | AKR1C3AKR1B10AKR1B1MMP2PAK1 | |
| Artepillin SCHEMBL1229229 | 0.83 | AKR1C3 (1.00) | AKR1C3AKR1B10AKR1B1MMP2PAK1 | |
| Artepillin SCHEMBL2138507 | 0.83 | AKR1C3 (1.00) | AKR1C3AKR1B10AKR1B1MMP2PAK1 | |
| Artepillin SCHEMBL7128580 | 0.83 | AKR1C3 (1.00) | AKR1C3AKR1B10AKR1B1MMP2PAK1 | |
| SCHEMBL10632283 | 0.83 | AKR1C3 (0.70) | AKR1C3AKR1B10AKR1B1MMP2PAK1 | |
| Stipulin SCHEMBL29435847 | 0.82 | PTPN1 (0.88) | AKR1C3AKR1B10AKR1B1MMP2PAK1 | |
| Stipulin SCHEMBL633709 | 0.82 | PTPN1 (0.88) | AKR1C3AKR1B10AKR1B1MMP2PAK1 | |
| SCHEMBL30384586 | 0.82 | PTPN1 (0.74) | AKR1C3AKR1B10AKR1B1PTPN1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4680720-A1 | OPTIMIZED PRODUCTION OF BRANCH POINT COMPOUNDS AND DERIVATIVES USING ALTERNATIVE ISOPENTENYL DIPHOSPHATE-SUPPLYING PATHWAYS | EvodiaBio ApS (DK) | 2026-01-21 | — | — | EP | claimed |
| US-12529077-B2 | Production of geranyl diphosphate-derived compounds | Københavns Universitet (DK) | 2026-01-20 | — | — | US | claimed |
| CN-119899829-A | Yarrowia lipolytica engineering bacterium for producing isopentenyl aromatic compound, construction method and application thereof | 山东大学 | 2025-04-29 | — | — | CN | claimed |
| US-20250041354-A1 | METHOD FOR TREATING BURN PAIN | IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) | 2025-02-06 | — | — | US | claimed |
| US-12150964-B1 | Subcutaneous injection method for pain treatment | IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) | 2024-11-26 | — | — | US | claimed |
| US-20240374653-A1 | SUBCUTANEOUS INJECTION METHOD FOR PAIN TREATMENT | IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) | 2024-11-14 | — | — | US | claimed |
| WO-2024189183-A1 | OPTIMIZED PRODUCTION OF BRANCH POINT COMPOUNDS AND DERIVATIVES USING ALTERNATIVE ISOPENTENYL DIPHOSPHATE-SUPPLYING PATHWAYS | EVODIABIO APS (DK) | 2024-09-19 | — | — | WO | claimed |
| US-12076349-B1 | Method for treating burns with brazilian green propolis | IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) | 2024-09-03 | — | — | US | claimed |
| US-20240277777-A1 | METHOD FOR TREATING BURNS WITH BRAZILIAN GREEN PROPOLIS | IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) | 2024-08-22 | — | — | US | claimed |
| US-11998572-B2 | Method for treating nociceptive pain and burns with brazilian green propolis alcohol extract | IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) | 2024-06-04 | — | — | US | claimed |
| CN-114377006-B | Absorption promoter for cinnamic acid derivative | 株式会社山田养蜂场本社 | 2024-02-09 | — | — | CN | claimed |
| US-20230159960-A1 | Production Of Geranyl Diphosphate-Derived Compounds | KOBENHAVNS UNIVERSITET (DK) | 2023-05-25 | — | — | US | claimed |
| EP-4133063-A1 | PRODUCTION OF GERANYL DIPHOSPHATE-DERIVED COMPOUNDS | Københavns Universitet (DK) | 2023-02-15 | — | — | EP | claimed |
| CN-115698272-A | Production of geranyl diphosphate derived compounds | 哥本哈根大学 | 2023-02-03 | — | — | CN | claimed |
| US-20220105054-A1 | ABSORPTION ENHANCER OF CINNAMIC ACID DERIVATIVE | YAMADA BEE COMPANY, INC. (JP) | 2022-04-07 | — | — | US | claimed |
| WO-2009111848-A1 | EXTRACTS OF BACCHARIS SP. OR GREEN PROPOLIS FOR USE AS SANITIZER | UNIVERSIDADE DE SÃO PAULO - USP (BR) | 2009-09-17 | — | — | WO | claimed |
| US-20060110520-A1 | Active oxygen eliminator derived from natural substance and use thereof | MIDORIKAWA KIYOSHI | 2006-05-25 | — | — | US | claimed |
| EP-1621194-A1 | ACTIVE OXYGEN ELIMINATOR ORIGINATING IN NATURAL MATERIAL AND USE OF THE SAME | Nihon Propolis Co., Ltd. (JP) | 2006-02-01 | — | — | EP | claimed |
| JP-60163841-A | — | — | None | — | — | JP | disclosed |
| JP-S60163841-A | 3-(4-HYDROXYPHENYL)-2-(E)-PROPENIC ACID | RES INST FOR PROD DEV | 1985-08-26 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12529077-B2 | Production of geranyl diphosphate-derived compounds | GGPS1, OGA, GBA3 | AKR1C3 253/4885AKR1B10 575/4885AKR1B1 439/4885 |
| US-20220105054-A1 | ABSORPTION ENHANCER OF CINNAMIC ACID DERIVATIVE | FABP2, SLC16A3, SLC16A7 | AKR1C3 261/4885AKR1B10 583/4885AKR1B1 363/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.