Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 13/20 | 1.00 |
| ▸ | AKR1B10 | O60218 | 3/20 | 1.00 |
| ▸ | AKR1B1 | P15121 | 3/20 | 1.00 |
| ▸ | MMP2 | P08253 | 2/20 | 0.71 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.71 |
| ▸ | AKR1C2 | P52895 | 11/20 | 0.67 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.67 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.65 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.65 |
| ▸ | MGAM | O43451 | 1/20 | 0.61 |
| ▸ | MAOA | P21397 | 1/20 | 0.61 |
| ▸ | MAOB | P27338 | 1/20 | 0.61 |
| ▸ | XDH | P47989 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Drupanin SCHEMBL3680290 | 1.00 | AKR1C3 (1.00) | AKR1C3AKR1B10AKR1B1MMP2PAK1 | |
| Drupanin SCHEMBL20472013 | 0.93 | AKR1C3 (0.87) | AKR1C3AKR1B10AKR1B1MMP2PAK1 | |
| Plicatin B SCHEMBL1227605 | 0.85 | AKR1C3 (0.73) | AKR1C3AKR1B10AKR1B1MMP2PAK1 | |
| Artepillin SCHEMBL1229229 | 0.83 | AKR1C3 (1.00) | AKR1C3AKR1B10AKR1B1MMP2PAK1 | |
| Artepillin SCHEMBL2138507 | 0.83 | AKR1C3 (1.00) | AKR1C3AKR1B10AKR1B1MMP2PAK1 | |
| Artepillin SCHEMBL7128580 | 0.83 | AKR1C3 (1.00) | AKR1C3AKR1B10AKR1B1MMP2PAK1 | |
| SCHEMBL10632283 | 0.83 | AKR1C3 (0.70) | AKR1C3AKR1B10AKR1B1MMP2PAK1 | |
| Stipulin SCHEMBL29435847 | 0.82 | PTPN1 (0.88) | AKR1C3AKR1B10AKR1B1MMP2PAK1 | |
| Stipulin SCHEMBL633709 | 0.82 | PTPN1 (0.88) | AKR1C3AKR1B10AKR1B1MMP2PAK1 | |
| SCHEMBL30384586 | 0.82 | PTPN1 (0.74) | AKR1C3AKR1B10AKR1B1PTPN1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060110520-A1 | Active oxygen eliminator derived from natural substance and use thereof | MIDORIKAWA KIYOSHI | 2006-05-25 | — | — | US | claimed |
| EP-1621194-A1 | ACTIVE OXYGEN ELIMINATOR ORIGINATING IN NATURAL MATERIAL AND USE OF THE SAME | Nihon Propolis Co., Ltd. (JP) | 2006-02-01 | — | — | EP | claimed |
| US-20230226003-A1 | NATURAL ANTIBACTERIAL AND ANTIVIRAL BIOLOGICAL COMPOSITIONS, COMPOUNDS, METHOD FOR OBTAINING SAME, AND USE THEREOF | BEEOTEC HOLDING S/A (BR) | 2023-07-20 | — | — | US | disclosed |
| CN-115942943-A | Natural antibacterial and antiviral biological compositions, compounds, methods of obtaining and uses thereof | 贝奥泰科控股股份有限公司 | 2023-04-07 | — | — | CN | disclosed |
| EP-4154895-A2 | NATURAL ANTIBACTERIAL AND ANTIVIRAL BIOLOGICAL COMPOSITIONS, COMPOUNDS, METHOD FOR OBTAINING SAME, AND USE THEREOF | Beeotec Holding S/A (BR) | 2023-03-29 | — | — | EP | disclosed |
| EP-1621194-A4 | ACTIVE OXYGEN ELIMINATOR ORIGINATING IN NATURAL MATERIAL AND USE OF THE SAME | NIHON PROPOLIS CO LTD (JP) | 2007-01-10 | — | — | EP | disclosed |
| US-20060110520-A1 | Active oxygen eliminator derived from natural substance and use thereof | MIDORIKAWA KIYOSHI | 2006-05-25 | — | — | US | disclosed |
| US-20060110520-A1 | Active oxygen eliminator derived from natural substance and use thereof | MIDORIKAWA KIYOSHI | 2006-05-25 | — | — | US | disclosed |
| EP-1621194-A1 | ACTIVE OXYGEN ELIMINATOR ORIGINATING IN NATURAL MATERIAL AND USE OF THE SAME | Nihon Propolis Co., Ltd. (JP) | 2006-02-01 | — | — | EP | disclosed |
| EP-1621194-A1 | ACTIVE OXYGEN ELIMINATOR ORIGINATING IN NATURAL MATERIAL AND USE OF THE SAME | Nihon Propolis Co., Ltd. (JP) | 2006-02-01 | — | — | EP | disclosed |
| EP-1575689-A2 | TYPING NATURAL PRODUCTS | Marcucci Ribeiro, Maria Cristina (BR) | 2005-09-21 | — | — | EP | disclosed |
| WO-2005067918-A1 | ACTIVE OXYGEN ELIMINATOR ORIGINATING IN NATURAL MATERIAL AND USE OF THE SAME | NIHON PROPOLIS CO., LTD. (JP) | 2005-07-28 | — | — | WO | disclosed |
| JP-2005200360-A | ACTIVE OXYGEN SCAVENGER DERIVED FROM NATURAL PRODUCT AND APPLICATION THEREOF | NIPPON PUROPORISU KK | 2005-07-28 | — | — | JP | disclosed |
| US-20040126437-A1 | Typing natural products | RIBEIRO MARIA CRISTINA MARCUCC (BR) | 2004-07-01 | — | — | US | disclosed |
| WO-2002051516-A2 | TYPING NATURAL PRODUCTS | MARCUCCI RIBEIRO MARIA CRISTIN (BR) | 2002-07-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230226003-A1 | NATURAL ANTIBACTERIAL AND ANTIVIRAL BIOLOGICAL COMPOSITIONS, COMPOUNDS, METHOD FOR OBTAINING SAME, AND USE THEREOF | NEFM, TNF, POLM | AKR1C3 4262/4885AKR1B10 3786/4885AKR1B1 4172/4885 |
| US-20040126437-A1 | Typing natural products | ACHE, BCHE, HLA-C | AKR1C3 429/4885AKR1B10 807/4885AKR1B1 964/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.