SCHEMBL3680645

SCHEMBL3680645

O=S(=O)(O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F.Sc1c(-c2ccccc2)c(-c2ccccc2)cc2ccccc12

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.38
KMT2A Q03164 5/20 0.38
RECQL P46063 1/20 0.38
GPR84 Q9NQS5 9/20 0.37
KDM4E B2RXH2 3/20 0.37
HPGD P15428 2/20 0.34
ALDH1A1 P00352 1/20 0.34
MAPT P10636 1/20 0.34
MPI P34949 1/20 0.34
ALOX5 P09917 1/20 0.34
PTPN1 P18031 1/20 0.33
PTGS2 P35354 1/20 0.32
ENPP1 P22413 1/20 0.32
CA1 P00915 3/20 0.31
CA2 P00918 3/20 0.31
LMNA P02545 1/20 0.31
MMP1 P03956 1/20 0.30
MMP2 P08253 1/20 0.30
MMP9 P14780 1/20 0.30
MMP8 P22894 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Perflubutane SCHEMBL6029410 0.93 MEN1 (0.41) MEN1KMT2ARECQLGPR84KDM4E
Trifluoromethanesulfonic Acid SCHEMBL547978 0.88 MEN1 (0.43) MEN1KMT2ARECQLGPR84KDM4E
SCHEMBL1041514 0.78 MEN1 (0.47) MEN1KMT2ARECQLGPR84KDM4E
SCHEMBL5040531 0.74 CDC14B (0.34) MAPT
SCHEMBL6063712 0.74 GPR84 (0.45) MEN1KMT2ARECQLGPR84KDM4E
Biphenyl SCHEMBL1816739 0.73 PTPN1 (0.47) PTPN1CA1CA2MMP1MMP2
SCHEMBL1516292 0.72 PLK1 (0.34) MAPTPTPN1CA1CA2MMP1
Benzenethiol SCHEMBL29745974 0.72 CA2 (0.39) PTPN1CA1CA2MMP1MMP2
SCHEMBL6271604 0.72 CA1 (0.36) PTPN1CA1CA2MMP1MMP2
SCHEMBL270057 0.71 PSD (0.36) GPR84ALOX5PTPN1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1788011-B1 Silicon-containing polymers and optical waveguides formed therefrom ROHM & HAAS ELECT MAT (US) 2013-01-09 EP disclosed
US-7693383-B2 Silicon-containing polymers and polymers and optical waveguides formed therefrom ROHM AND HAAS ELECTRONICS MATERIALS (US) 2010-04-06 US disclosed
EP-1772482-B1 Waveguide compositions and waveguides formed therefrom ROHM & HAAS ELECT MAT (US) 2009-06-17 EP disclosed
EP-1586603-B1 Waveguide compositions and waveguides formed therefrom ROHM & HAAS ELECT MAT (US) 2007-06-13 EP disclosed
EP-1788011-A2 Silicon-containing polymers and optical waveguides formed therefrom Rohm and Haas Electronic Materials, L.L.C. (US) 2007-05-23 EP disclosed
US-20070107629-A1 Silicon-containing polymers and polymers and optical waveguides formed therefrom ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2007-05-17 US disclosed
EP-1772482-A1 Waveguide compositions and waveguides formed therefrom Rohm and Haas Electronic Materials, L.L.C. (US) 2007-04-11 EP disclosed
US-7072565-B2 Waveguide compositions and waveguides formed therefrom ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2006-07-04 US disclosed
US-7072563-B2 Waveguide compositions and waveguides formed therefrom ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2006-07-04 US disclosed
US-20050244124-A1 Waveguide compositions and waveguides formed therefrom ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2005-11-03 US disclosed
EP-1586603-A1 Waveguide compositions and waveguides formed therefrom Rohm and Haas Electronic Materials LLC (US) 2005-10-19 EP disclosed
US-20050141839-A1 Waveguide compositions and waveguides formed therefrom ROHM AND HAAS ELECTRONIC MATERIALS, L.L.C. (US) 2005-06-30 US disclosed
EP-1535977-A1 Waveguide compositions and waveguides formed therefrom. Rohm and Haas Electronic Materials, L.L.C. (US) 2005-06-01 EP disclosed