SCHEMBL3681004

SCHEMBL3681004

Cc1cnoc1C(=O)N[C@@H]1CCCc2ccccc21

nearest known ligand 0.72

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TAS1R3 Q7RTX0 8/20 0.72
TAS1R1 Q7RTX1 8/20 0.72
TAS1R2 Q8TE23 6/20 0.72
TSHR P16473 2/20 0.64
RECQL P46063 1/20 0.62
LMNA P02545 2/20 0.61
MAPT P10636 1/20 0.61
SMN1; SMN2 Q16637 1/20 0.61
ALDH1A1 P00352 4/20 0.60
HSD17B10 Q99714 2/20 0.60
HTT P42858 1/20 0.58
CNR1 P21554 1/20 0.56
CNR2 P34972 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3638553 1.00 TAS1R3 (0.72) TAS1R3TAS1R1TAS1R2TSHRRECQL
SCHEMBL701176 0.84 TAS1R3 (1.00) TAS1R3TAS1R1TAS1R2TSHRRECQL
SCHEMBL701177 0.84 TAS1R3 (1.00) TAS1R3TAS1R1TAS1R2TSHRRECQL
SCHEMBL701434 0.78 TAS1R3 (1.00) TAS1R3TAS1R1TAS1R2TSHRRECQL
SCHEMBL701435 0.78 TAS1R3 (1.00) TAS1R3TAS1R1TAS1R2TSHRRECQL
SCHEMBL3674373 0.77 ALDH1A1 (0.63) TAS1R3TAS1R1TAS1R2TSHRRECQL
SCHEMBL3641608 0.77 ALDH1A1 (0.63) TAS1R3TAS1R1TAS1R2TSHRRECQL
SCHEMBL6515820 0.77 LMNA (0.61) TAS1R3TAS1R1TAS1R2TSHRRECQL
SCHEMBL6513453 0.77 LMNA (0.61) TAS1R3TAS1R1TAS1R2TSHRRECQL
SCHEMBL3388821 0.76 POLB (0.67) TAS1R3TAS1R1TAS1R2TSHRRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8709521-B2 Sweetener compositions having enhanced sweetness and improved temporal and/or flavor profiles THE COCA-COLA COMPANY (US) 2014-04-29 US claimed
EP-2160103-A1 SWEETENER COMPOSITIONS HAVING ENHANCED SWEETNESS AND IMPROVED TEMPORAL AND/OR FLAVOR PROFILES THE COCA-COLA COMPANY (US) 2010-03-10 EP claimed
US-20090053378-A1 Sweetener Compositions Having Enhanced Sweetness and Improved Temporal and/or Flavor Profiles THE COCA-COLA COMPANY (US) 2009-02-26 US claimed
WO-2008147726-A1 SWEETENER COMPOSITIONS HAVING ENHANCED SWEETNESS AND IMPROVED TEMPORAL AND/OR FLAVOR PROFILES THE COCA-COLA COMPANY (US) 2008-12-04 WO claimed
EP-2160103-B1 SWEETENER COMPOSITIONS HAVING ENHANCED SWEETNESS AND IMPROVED TEMPORAL AND/OR FLAVOR PROFILES COCA COLA CO (US) 2015-07-29 EP disclosed
US-8709521-B2 Sweetener compositions having enhanced sweetness and improved temporal and/or flavor profiles THE COCA-COLA COMPANY (US) 2014-04-29 US disclosed
EP-2160103-A1 SWEETENER COMPOSITIONS HAVING ENHANCED SWEETNESS AND IMPROVED TEMPORAL AND/OR FLAVOR PROFILES THE COCA-COLA COMPANY (US) 2010-03-10 EP disclosed
US-20090053378-A1 Sweetener Compositions Having Enhanced Sweetness and Improved Temporal and/or Flavor Profiles THE COCA-COLA COMPANY (US) 2009-02-26 US disclosed
WO-2008147726-A1 SWEETENER COMPOSITIONS HAVING ENHANCED SWEETNESS AND IMPROVED TEMPORAL AND/OR FLAVOR PROFILES THE COCA-COLA COMPANY (US) 2008-12-04 WO disclosed