SCHEMBL3681070

SCHEMBL3681070

O=C(CCl)OCC(OC(=O)CCl)C(OC(=O)CCl)C(OC(=O)CCl)C(COC(=O)CCl)OC(=O)CCl

nearest known ligand 0.42

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3675625 0.96 TDP1 (0.38) TDP1
SCHEMBL3677069 0.89 TDP1 (0.33) TDP1
SCHEMBL14657907 0.87 TDP1 (0.34) TDP1
SCHEMBL2585304 0.76 ALDH1A1 (0.46)
SCHEMBL30596868 0.75 TDP1 (0.47) TDP1
SCHEMBL12154411 0.75 TDP1 (0.47) TDP1
SCHEMBL10736810 0.75 TDP1 (0.42) TDP1
SCHEMBL16500282 0.75 TDP1 (0.47) TDP1
SCHEMBL31068996 0.73 TDP1 (0.50) TDP1
SCHEMBL20577612 0.73 TDP1 (0.50) TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2013240-B1 PROCESS FOR THE PREPARATION OF CROSSLINKED NITROXIDE POLYMERS PIOTREK CO LTD (JP) 2017-05-31 EP disclosed
US-8492511-B2 Process for the preparation of crosslinked nitroxide polymers PIOTREK CO., LTD. (JP) 2013-07-23 US disclosed
US-20100240858-A1 PROCESS FOR THE PREPARATION OF CROSSLINKED NITROXIDE POLYMERS PIOTREK CO., LTD. (JP) 2010-09-23 US disclosed
EP-2013240-A1 PROCESS FOR THE PREPARATION OF CROSSLINKED NITROXIDE POLYMERS PIOTREK CO., LTD. (JP) 2009-01-14 EP disclosed
WO-2007115939-A1 PROCESS FOR THE PREPARATION OF CROSSLINKED NITROXIDE POLYMERS PIOTREK CO., LTD. (JP) 2007-10-18 WO disclosed