SCHEMBL3675625

SCHEMBL3675625

O=C(CCl)OCC(OC(=O)CCl)C(OC(=O)CCl)C(COC(=O)CCl)OC(=O)CCl

nearest known ligand 0.38

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3681070 0.96 TDP1 (0.42) TDP1
SCHEMBL3677069 0.89 TDP1 (0.33) TDP1
SCHEMBL14657907 0.83 TDP1 (0.34) TDP1
SCHEMBL2585304 0.76 ALDH1A1 (0.46)
SCHEMBL16500255 0.75 TDP1 (0.42) TDP1
SCHEMBL10877359 0.72
SCHEMBL11686114 0.72 FAAH (0.39) TDP1
SCHEMBL9344397 0.72 TDP1 (0.36) TDP1
SCHEMBL4914069 0.72 ALDH1A1 (0.47) TDP1
SCHEMBL30443221 0.72 TDP1 (0.48) TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2013240-B1 PROCESS FOR THE PREPARATION OF CROSSLINKED NITROXIDE POLYMERS PIOTREK CO LTD (JP) 2017-05-31 EP disclosed
US-8492511-B2 Process for the preparation of crosslinked nitroxide polymers PIOTREK CO., LTD. (JP) 2013-07-23 US disclosed
US-20100240858-A1 PROCESS FOR THE PREPARATION OF CROSSLINKED NITROXIDE POLYMERS PIOTREK CO., LTD. (JP) 2010-09-23 US disclosed
EP-2013240-A1 PROCESS FOR THE PREPARATION OF CROSSLINKED NITROXIDE POLYMERS PIOTREK CO., LTD. (JP) 2009-01-14 EP disclosed
WO-2007115939-A1 PROCESS FOR THE PREPARATION OF CROSSLINKED NITROXIDE POLYMERS PIOTREK CO., LTD. (JP) 2007-10-18 WO disclosed