Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.60 |
| ▸ | TNKS | O95271 | 4/20 | 0.60 |
| ▸ | MAOB | P27338 | 3/20 | 0.59 |
| ▸ | CA12 | O43570 | 2/20 | 0.59 |
| ▸ | CA1 | P00915 | 2/20 | 0.59 |
| ▸ | CA2 | P00918 | 2/20 | 0.59 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.59 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.59 |
| ▸ | CA9 | Q16790 | 2/20 | 0.59 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.59 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.59 |
| ▸ | MAOA | P21397 | 1/20 | 0.59 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.59 |
| ▸ | XDH | P47989 | 1/20 | 0.59 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 4/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3690167 | 0.89 | PLA2G2A (0.64) | CYP19A1TNKSCA12CA1CA2 | |
| SCHEMBL20582108 | 0.86 | TNKS (0.72) | CYP19A1TNKSMAOBCA12CA1 | |
| SCHEMBL20582109 | 0.83 | CYP19A1 (0.62) | CYP19A1TNKSMAOBCA12CA1 | |
| SCHEMBL7621719 | 0.82 | MAOB (0.62) | CYP19A1TNKSMAOBCA12CA1 | |
| SCHEMBL2860377 | 0.78 | ALDH1A1 (0.40) | TNKSMAOBCYP1B1CYP1A2TP53 | |
| 7-Methylflavone SCHEMBL9137885 | 0.78 | TP53 (0.77) | CYP19A1TNKSMAOBCA12CA1 | |
| SCHEMBL22032720 | 0.77 | QPCT (0.79) | CYP19A1TNKSMAOBMAOACYP3A4 | |
| 7-Methoxyflavone SCHEMBL1373009 | 0.75 | TNKS (1.00) | CYP19A1TNKSMAOBABCB1TP53 | |
| SCHEMBL22084009 | 0.75 | CYP19A1 (0.54) | CYP19A1TNKSMAOBCA12CA1 | |
| Flavone SCHEMBL15676601 | 0.75 | TNKS (1.00) | CYP19A1TNKSMAOBCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2231720-B1 | FUNCTIONALIZED POLYMER AND METHODS FOR MAKING AND USING | BRIDGESTONE CORP (JP) | 2013-08-14 | — | — | EP | disclosed |
| US-8236892-B2 | Functionalized polymer and methods for making and using | BRIDGESTONE CORPORATION (JP) | 2012-08-07 | — | — | US | disclosed |
| US-20100311899-A1 | FUNCTIONALIZED POLYMER AND METHODS FOR MAKING AND USING | BRIDGESTONE CORPORATION (JP) | 2010-12-09 | — | — | US | disclosed |