Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.51 |
| ▸ | KDM1A | O60341 | 2/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.49 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.49 |
| ▸ | WNT3A | P56704 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29410879 | 1.00 | ALDH1A1 (0.62) | ALDH1A1MEN1KMT2ANPC1MAPT | |
| SCHEMBL16526953 | 0.98 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2ANPC1MAPT | |
| Hydrochloric Acid SCHEMBL28389380 | 0.98 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2ANPC1MAPT | |
| SCHEMBL1719205 | 0.96 | ALDH1A1 (0.68) | ALDH1A1MEN1KMT2ANPC1MAPT | |
| SCHEMBL29543577 | 0.96 | ALDH1A1 (0.68) | ALDH1A1MEN1KMT2ANPC1MAPT | |
| SCHEMBL21168435 | 0.91 | HSD17B3 (0.55) | ALDH1A1MEN1KMT2ANPC1MAPT | |
| Sulfuric Acid SCHEMBL27798096 | 0.89 | ALDH1A1 (0.59) | ALDH1A1MEN1KMT2ANPC1MAPT | |
| Trifluoroacetic Acid SCHEMBL7423059 | 0.88 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2ANPC1MAPT | |
| SCHEMBL10539670 | 0.88 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2ANPC1MAPT | |
| Glycine SCHEMBL7128369 | 0.86 | ALDH1A1 (0.61) | ALDH1A1MEN1KMT2ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2280933-A1 | 2 -AMINOTETRALIN DERIVATIVES AS MU OPIOID RECEPTOR ANTAGONISTS | Theravance, Inc. (US) | 2011-02-09 | — | — | EP | claimed |
| US-6936173-B2 | Carbohydrate purification using ultrafiltration, reverse osmosis and nanofiltration | NEOSE TECHNOLOGIES, INC. (US) | 2005-08-30 | — | — | US | claimed |
| US-20030029799-A1 | Carbohydrate purification using ultrafiltration, reverse osmosis and nanofiltration | NEOSE TECHNOLOGIES | 2003-02-13 | — | — | US | claimed |
| US-20020148791-A1 | Carbohydrate purification using ultrafiltration, reverse osmosis and nanofiltration | NEOSE TECHNOLOGIES (US) | 2002-10-17 | — | — | US | claimed |
| JP-2001502005-A | — | — | 2001-02-13 | — | — | JP | claimed |
| EP-0931097-A4 | CARBOHYDRATE PURIFICATION USING ULTRAFILTRATION, REVERSE OSMOSIS AND NANOFILTRATION | CYTEL CORP (US) | 2000-01-12 | — | — | EP | claimed |
| EP-0931097-A1 | CARBOHYDRATE PURIFICATION USING ULTRAFILTRATION, REVERSE OSMOSIS AND NANOFILTRATION | CYTEL CORPORATION (US) | 1999-07-28 | — | — | EP | claimed |
| WO-1998015581-A1 | CARBOHYDRATE PURIFICATION USING ULTRAFILTRATION, REVERSE OSMOSIS AND NANOFILTRATION | CYTEL CORPORATION (US) | 1998-04-16 | — | — | WO | claimed |
| EP-3394068-B1 | TDO2 INHIBITORS | GENENTECH INC (US) | 2024-09-11 | — | — | EP | disclosed |
| US-20230101819-A1 | SMYD Inhibitors | EPIZYME INC (US) | 2023-03-30 | — | — | US | disclosed |
| US-20220306635-A1 | TDO2 Inhibitors | GENENTECH, INC. | 2022-09-29 | — | — | US | disclosed |
| WO-2021198283-A1 | INHIBITORS OF ANTIGEN PRESENTATION BY HLA-DR | JANSSEN PHARMACEUTICA NV (BE) | 2021-10-07 | — | — | WO | disclosed |
| US-20210198252-A1 | SMYD INHIBITORS | EPIZYME INC (US) | 2021-07-01 | — | — | US | disclosed |
| CN-107207416-B | Novel adamantane derivative compound | 株式会社爱茉莉太平洋 | 2020-02-07 | — | — | CN | disclosed |
| EP-0820519-A1 | ENZYMATIC SYNTHESIS OF GLYCOSIDIC LINKAGES | CYTEL CORPORATION (US) | 1998-01-28 | — | — | EP | disclosed |
| EP-0820520-A1 | IMPROVED ENZYMATIC SYNTHESIS OF OLIGOSACCHARIDES | CYTEL CORPORATION (US) | 1998-01-28 | — | — | EP | disclosed |
| WO-1996032491-A1 | ENZYMATIC SYNTHESIS OF GLYCOSIDIC LINKAGES | CYTEL CORPORATION (US) | 1996-10-17 | — | — | WO | disclosed |
| WO-1996032492-A1 | IMPROVED ENZYMATIC SYNTHESIS OF OLIGOSACCHARIDES | CYTEL CORPORATION (US) | 1996-10-17 | — | — | WO | disclosed |
| EP-0666250-A1 | Derivatives of N-(3-aminopropyl)-N-phenyl-5,6,7,8-tetrahydronaphthalene-2-carboxamide having neuroprotective and anti-ischemic properties, their preparation and their use, in therapy | SYNTHELABO (FR) | 1995-08-09 | — | — | EP | disclosed |
| US-4282212-A | Immune-stimulating 1-(N-acylcarbamoyl)-2-cyanoaziridines | BOEHRINGER MANNHEIM GMBH (DE) | 1981-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210198252-A1 | SMYD INHIBITORS | SMYD3, SMYD2, SMURF2 | ALDH1A1 1575/4885MEN1 3280/4885KMT2A 355/4885 |
| US-20220306635-A1 | TDO2 Inhibitors | TDO2, IDO2, IDO1 | ALDH1A1 1849/4885MEN1 4540/4885KMT2A 664/4885 |
| US-20020148791-A1 | Carbohydrate purification using ultrafiltration, reverse osmosis and nanofiltration | OSTC, TREH, MGAM | ALDH1A1 1873/4885MEN1 4409/4885KMT2A 4465/4885 |
| US-20230101819-A1 | SMYD Inhibitors | SMYD3, SMYD2, SMURF2 | ALDH1A1 1611/4885MEN1 3330/4885KMT2A 364/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.