SCHEMBL3682124

SCHEMBL3682124

COC(C)(C)C(=O)c1ccc(C(C)c2ccc(C(=O)C(C)(C)OC)cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.39
PDCD1 Q15116 1/20 0.39
ESR2 Q92731 1/20 0.39
CD274 Q9NZQ7 1/20 0.39
MLYCD O95822 4/20 0.39
CES1 P23141 1/20 0.37
RXRA P19793 1/20 0.36
RXRB P28702 1/20 0.36
NR1H4 Q96RI1 2/20 0.34
CYP2C9 P11712 2/20 0.33
RAB9A P51151 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
SRC P12931 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
USP5 P45974 1/20 0.33
ELANE P08246 1/20 0.33
CYP3A4 P08684 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9246353 0.89 CYP2C9 (0.44) MLYCDRXRARXRBCYP2C9RAB9A
SCHEMBL4425629 0.84 CES1 (0.36) ESR1ESR2MLYCDCES1NR1H4
SCHEMBL10712634 0.79 TDP1 (0.52) CES1RAB9ANPSR1HDAC1HDAC6
SCHEMBL4197514 0.79 ESR1 (0.43) ESR1PDCD1ESR2CD274MLYCD
SCHEMBL11299913 0.77 CES1 (0.46) CES1RAB9A
SCHEMBL6676984 0.77 PPARA (0.49) CES1CYP2C9RAB9ANPSR1ELANE
SCHEMBL6448136 0.77 ESR1 (0.41) ESR1PDCD1ESR2CD274MLYCD
SCHEMBL18678827 0.77 TPMT (0.45) MLYCDCES1RXRARXRBSRC
SCHEMBL20135443 0.77 CA1 (0.55) RAB9AL3MBTL1TSHR
SCHEMBL3689915 0.77 HPGD (0.52) CES1RAB9AELANETSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1523506-B1 NEW DIFUNCTIONAL PHOTOINITIATORS BASF SE (DE) 2012-09-12 EP disclosed
EP-1523506-B1 NEW DIFUNCTIONAL PHOTOINITIATORS BASF SE (DE) 2012-09-12 EP disclosed
US-7723397-B2 ethylenically unsaturated aminoacrylates; overprinting; for production of scratch-resistant durable surface CIBA SPECIALTY CHEMICALS CORPORATION (US) 2010-05-25 US disclosed
US-7723397-B2 ethylenically unsaturated aminoacrylates; overprinting; for production of scratch-resistant durable surface CIBA SPECIALTY CHEMICALS CORPORATION (US) 2010-05-25 US disclosed
US-7723397-B2 ethylenically unsaturated aminoacrylates; overprinting; for production of scratch-resistant durable surface CIBA SPECIALTY CHEMICALS CORPORATION (US) 2010-05-25 US disclosed
US-20050239971-A1 New difunctional photoinitators IGM GROUP B.V. (NL) 2005-10-27 US disclosed
EP-1523506-A1 NEW DIFUNCTIONAL PHOTOINITIATORS Ciba SC Holding AG (CH) 2005-04-20 EP disclosed
WO-2004009651-A1 NEW DIFUNCTIONAL PHOTOINITIATORS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-01-29 WO disclosed