Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | MLYCD | O95822 | 5/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | USP5 | P45974 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10752558 | 0.88 | CYP2C9 (0.47) | RXRARXRBPOLBCYP2C9USP5 | |
| SCHEMBL27625178 | 0.85 | MLYCD (0.36) | MLYCDNR1H4POLBCYP2C9HDAC1 | |
| SCHEMBL27645545 | 0.82 | GSK3B (0.35) | MLYCDNR1H4POLBCYP2C9HDAC1 | |
| SCHEMBL480373 | 0.82 | GSK3B (0.35) | MLYCDNR1H4POLBCYP2C9HDAC1 | |
| SCHEMBL4197514 | 0.82 | ESR1 (0.43) | ESR1PDCD1ESR2CD274RXRA | |
| SCHEMBL4427192 | 0.79 | RARA (0.35) | ESR1ESR2MLYCDL3MBTL1CHEK2 | |
| SCHEMBL4421929 | 0.79 | ALDH1A1 (0.48) | ESR1ESR2ALDH1A1LMNAHPGD | |
| SCHEMBL3682124 | 0.77 | ESR1 (0.39) | ESR1PDCD1ESR2CD274RXRA | |
| SCHEMBL10710376 | 0.77 | CA2 (0.53) | HDAC1HDAC6MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10887646 | 0.77 | CES2 (0.52) | POLBL3MBTL1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1523506-A1 | NEW DIFUNCTIONAL PHOTOINITIATORS | Ciba SC Holding AG (CH) | 2005-04-20 | — | — | EP | disclosed |
| WO-2004009651-A1 | NEW DIFUNCTIONAL PHOTOINITIATORS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2004-01-29 | — | — | WO | disclosed |