SCHEMBL3682182

SCHEMBL3682182

O=Nc1ccc2nc3ccccc3nc2c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO2 P16083 5/20 0.50
MAPT P10636 9/20 0.48
MEN1 O00255 6/20 0.46
KMT2A Q03164 6/20 0.46
NPC1 O15118 5/20 0.46
POLB P06746 2/20 0.46
USP2 O75604 1/20 0.46
CACNA1B Q00975 1/20 0.46
APBA1 Q02410 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
ALDH1A1 P00352 7/20 0.44
RAB9A P51151 4/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
KDM4E B2RXH2 3/20 0.44
LMNA P02545 3/20 0.44
HSD17B10 Q99714 3/20 0.42
TDP1 Q9NUW8 3/20 0.42
CYP3A4 P08684 2/20 0.42
TSHR P16473 2/20 0.42
HTT P42858 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13904021 0.81 TDP1 (0.44) MAPTMEN1KMT2AUSP2L3MBTL1
SCHEMBL8820259 0.78 NQO2 (0.50) NQO2MAPTMEN1KMT2ANPC1
SCHEMBL22416822 0.77 MEN1 (0.44) MAPTMEN1KMT2ANPC1ALDH1A1
SCHEMBL28852256 0.77 ALDH1A1 (0.42) MAPTMEN1KMT2AALDH1A1KDM4E
SCHEMBL15761575 0.76 MAOA (0.60) NQO2MAPTMEN1KMT2APOLB
SCHEMBL15761577 0.76 ALDH1A1 (0.60) NQO2MAPTKMT2ANPC1POLB
SCHEMBL12344237 0.74 USP7 (0.31) MAPTMEN1KMT2AALDH1A1LMNA
SCHEMBL4612924 0.72 MAPT (0.79) NQO2MAPTMEN1KMT2ANPC1
SCHEMBL13156546 0.72 MAPT (0.79) NQO2MAPTMEN1KMT2ANPC1
SCHEMBL29614768 0.72 MAPT (0.79) NQO2MAPTMEN1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8623967-B2 Polymers functionalized with nitroso compounds BRIDGESTONE CORPORATION (JP) 2014-01-07 US claimed
US-20130096264-A1 POLYMERS FUNCTIONALIZED WITH NITROSO COMPOUNDS BRIDGESTONE CORPORATION (JP) 2013-04-18 US claimed
US-8188195-B2 Polymers functionalized with nitroso compounds BRIDGESTONE CORPORATION (JP) 2012-05-29 US claimed
US-20100168378-A1 POLYMERS FUNCTIONALIZED WITH NITROSO COMPOUNDS BRIDGESTONE CORPORATION (JP) 2010-07-01 US claimed
US-9670299-B2 Polymers functionalized with nitroso compounds BRIDGESTONE CORPORATION (JP) 2017-06-06 US disclosed
US-20160032030-A1 POLYMERS FUNCTIONALIZED WITH NITROSO COMPOUNDS BRIDGESTONE CORPORATION (JP) 2016-02-04 US disclosed
US-9127100-B2 Polymers functionalized with nitroso compounds BRIDGESTONE CORPORATION (JP) 2015-09-08 US disclosed
US-20140100340-A1 POLYMERS FUNCTIONALIZED WITH NITROSO COMPOUNDS BRIDGESTONE CORPORATION (JP) 2014-04-10 US disclosed
US-8623967-B2 Polymers functionalized with nitroso compounds BRIDGESTONE CORPORATION (JP) 2014-01-07 US disclosed
US-20130096264-A1 POLYMERS FUNCTIONALIZED WITH NITROSO COMPOUNDS BRIDGESTONE CORPORATION (JP) 2013-04-18 US disclosed
US-8188195-B2 Polymers functionalized with nitroso compounds BRIDGESTONE CORPORATION (JP) 2012-05-29 US disclosed
US-20100168378-A1 POLYMERS FUNCTIONALIZED WITH NITROSO COMPOUNDS BRIDGESTONE CORPORATION (JP) 2010-07-01 US disclosed