Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 5/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8403545 | 0.87 | POLB (0.61) | POLBCA2KMT2ACAMK2AALDH1A1 | |
| SCHEMBL8986864 | 0.81 | POLB (0.52) | POLBCA2KMT2ACAMK2AALDH1A1 | |
| SCHEMBL15251712 | 0.80 | IDO1 (0.46) | IDO1FOLH1CA2CAMK2AANPEP | |
| SCHEMBL10775630 | 0.80 | POLB (0.55) | POLBCA2KMT2ACAMK2AALDH1A1 | |
| SCHEMBL8277240 | 0.78 | CA2 (0.62) | POLBCA2KMT2ACAMK2AANPEP | |
| SCHEMBL2357364 | 0.78 | CA2 (0.62) | POLBIDO1FOLH1CA2KMT2A | |
| SCHEMBL4455 | 0.78 | CA2 (0.62) | POLBIDO1CA2CAMK2AALDH1A1 | |
| SCHEMBL81559 | 0.78 | CTBP2 (0.53) | POLBKMT2AALDH1A1HPGDLMNA | |
| SCHEMBL9149413 | 0.78 | POLB (0.53) | POLBCA2KMT2ACAMK2AALDH1A1 | |
| SCHEMBL5536012 | 0.78 | POLB (0.53) | POLBCA2KMT2ACAMK2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014183221-A1 | RESVERATROL ANALOGS AND THERAPEUTIC USES THEREOF | THE CENTRE FOR DRUG RESEARCH AND DEVELOPMENT (CA) | 2014-11-20 | — | — | WO | disclosed |
| EP-2185621-A1 | CURABLE RESIN COMPOSITION FOR MOLDED BODIES, MOLDED BODY, AND PRODUCTION METHOD THEREOF | Nippon Shokubai Co., Ltd. (JP) | 2010-05-19 | — | — | EP | disclosed |
| WO-2009041711-A1 | CURABLE RESIN COMPOSITION FOR MOLDED BODIES, MOLDED BODY, AND PRODUCTION METHOD THEREOF | NIPPON SHOKUBAI CO., LTD. (JP) | 2009-04-02 | — | — | WO | disclosed |
| EP-1288206-B1 | Substituted benzenesulfonamide derivatives as prodrugs of COX-2 inhibitors | SEARLE LLC (US) | 2008-09-17 | — | — | EP | disclosed |