Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8403545 | 0.87 | POLB (0.61) | POLBCA2KMT2ACAMK2AALDH1A1 | |
| SCHEMBL3682459 | 0.81 | POLB (0.52) | POLBCA2KMT2ACAMK2AALDH1A1 | |
| SCHEMBL10775630 | 0.80 | POLB (0.55) | POLBCA2KMT2ACAMK2AALDH1A1 | |
| SCHEMBL564730 | 0.78 | ALDH1A1 (0.54) | POLBCA2KMT2AALDH1A1HPGD | |
| SCHEMBL1527709 | 0.78 | CA2 (0.62) | POLBCA2KMT2ACAMK2AALDH1A1 | |
| SCHEMBL9149413 | 0.78 | POLB (0.53) | POLBCA2KMT2ACAMK2AALDH1A1 | |
| SCHEMBL4455 | 0.78 | CA2 (0.62) | POLBCA2CAMK2AALDH1A1LMNA | |
| SCHEMBL81559 | 0.78 | CTBP2 (0.53) | POLBKMT2AALDH1A1HPGDLMNA | |
| SCHEMBL165930 | 0.78 | CA2 (0.62) | POLBCA2KMT2ACAMK2AALDH1A1 | |
| SCHEMBL5536012 | 0.78 | POLB (0.53) | POLBCA2KMT2ACAMK2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3749355-B1 | INHIBITORS OF THE NOTCH TRANSCRIPTIONAL ACTIVATION COMPLEX KINASE (\"NACK\") AND METHODS FOR USE OF THE SAME | UNIV MIAMI (US) | 2024-07-03 | — | — | EP | disclosed |
| US-20200385328-A1 | METHOD FOR PRODUCING BENZOYL FORMIC ACID COMPOUND AND PYRIDAZINE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2020-12-10 | — | — | US | disclosed |
| US-20180086739-A1 | PLK4 INHIBITORS | LUDWIG INSTITUTE FOR CANCER RESEARCH LTD (CH) | 2018-03-29 | — | — | US | disclosed |
| US-20130274256-A1 | NOVEL INHIBITORS OF BACTERIAL BIOFILMS AND RELATED METHODS | SEQUOIA SCIENCES, INC. (US) | 2013-10-17 | — | — | US | disclosed |
| EP-0375422-B1 | Composition and methods for determining the presence of amphetamines in a sample suspected of containing amphetamine and/or methamphetamine | BEHRINGWERKE AG (DE) | 1996-07-03 | — | — | EP | disclosed |
| US-5328828-A | Immunoassay for amphetamines with antibodies for conjugation and enzymes | SYNTEX (U.S.A.) INC. (US) | 1994-07-12 | — | — | US | disclosed |
| US-5135863-A | Immunoassay; drug abuse | SYNTEX (U.S.A.) INC. (US) | 1992-08-04 | — | — | US | disclosed |
| EP-0375422-A2 | Composition and methods for determining the presence of amphetamines in a sample suspected of containing amphetamine and/or methamphetamine | BEHRINGWERKE Aktiengesellschaft (DE) | 1990-06-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180086739-A1 | PLK4 INHIBITORS | PLK4, PLK2, PLK3 | POLB 801/4885CA2 4570/4885KMT2A 1312/4885 |
| US-20200385328-A1 | METHOD FOR PRODUCING BENZOYL FORMIC ACID COMPOUND AND PYRIDAZINE COMPOUND | SDHA, FDPS, NDUFS5 | POLB 583/4885CA2 1311/4885KMT2A 2197/4885 |
| US-20130274256-A1 | NOVEL INHIBITORS OF BACTERIAL BIOFILMS AND RELATED METHODS | BLVRB, MMP8, PGLS | POLB 725/4885CA2 1504/4885KMT2A 3949/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.