Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 10/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2495228 | 0.87 | EPHX1 (0.56) | EPHX1ACHE | |
| SCHEMBL789713 | 0.79 | HSD17B10 (0.47) | EPHX1MAPTCES2GMNNTP53 | |
| SCHEMBL10529861 | 0.78 | HSD17B10 (0.50) | EPHX1MAPTCES2GMNNTP53 | |
| SCHEMBL6907432 | 0.78 | HSD17B10 (0.50) | EPHX1MAPTCES2GMNNTP53 | |
| SCHEMBL1276540 | 0.75 | CES2 (0.47) | EPHX1ACHEMAPTCES2GMNN | |
| SCHEMBL11293412 | 0.74 | CES2 (0.45) | EPHX1MAPTCES2GMNNTP53 | |
| SCHEMBL561899 | 0.74 | EPHX1 (0.46) | EPHX1MAPTCES2GMNNTP53 | |
| SCHEMBL28348544 | 0.73 | EPHX1 (0.52) | EPHX1CES2POLBHSD17B10MEN1 | |
| Carbamic Acid SCHEMBL29232548 | 0.73 | EPHX1 (0.46) | EPHX1MAPTCES2GMNNTP53 | |
| SCHEMBL8207874 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4709016-A | Molecular analytical release tags and their use in chemical analysis | NORTHEASTERN UNIVERSITY (US) | 1987-11-24 | — | — | US | claimed |
| EP-1809726-B1 | USE OF 1,3-DITHIOLANE-2-THIONE ADDITIVES FOR LUBRICANTS | LANXESS SOLUTIONS US INC (US) | 2019-08-28 | — | — | EP | disclosed |
| EP-1833951-B1 | DITHIOCARBAMYL ß-HYDROXY FATTY ACID ESTERS AS ADDITIVES FOR LUBRICANTS AND FUELS | CHEMTURA CORP (US) | 2012-08-22 | — | — | EP | disclosed |
| US-8097731-B2 | Reaction products of mercaptobenzothiazoles, mercaptothiazolines, and mercaptobenzimidalzoles with epoxides as lubricant additives | CROMPTON CORPORATION (US) | 2012-01-17 | — | — | US | disclosed |
| US-8048832-B2 | 1,3 dithiolane-2-thione additives for lubricants and fuels | CHEMTURA CORPORATION (US) | 2011-11-01 | — | — | US | disclosed |
| EP-2314661-A1 | Lubricant and fuel compositions containing hydroxy polycarboxylic acid esters | Chemtura Corporation (US) | 2011-04-27 | — | — | EP | disclosed |
| EP-1654342-B1 | REACTION PRODUCTS OF MERCAPTOBENZOTHIAZOLES, MERCAPTOTHIAZOLINES, AND MERCAPTOBENZIMIDAZOLES WITH EPOXIDES AS LUBRICANT ADDITIVES | CHEMTURA CORP (US) | 2011-01-19 | — | — | EP | disclosed |
| US-7696136-B2 | Lubricant compositions containing hydroxy carboxylic acid and hydroxy polycarboxylic acid esters | CROMPTON CORPORATION (US) | 2010-04-13 | — | — | US | disclosed |
| US-20090181870-A1 | 1,3 DITHIOLANE-2-THIONE ADDITIVES FOR LUBRICANTS AND FUELS | CHEMTURA CORPORATION (US) | 2009-07-16 | — | — | US | disclosed |
| US-7541319-B2 | 1,3-dithiolane-2-thione additives for lubricants and fuels | CHEMTURA CORPORATION (US) | 2009-06-02 | — | — | US | disclosed |
| WO-2001036572-A1 | SUBSTITUTED LINEAR THIOUREA COMPOUNDS AS ADDITIVES FOR LUBRICANTS | CROMPTON CORPORATION (US) | 2001-05-25 | — | — | WO | disclosed |
| US-6187726-B1 | ALKYL ETHER OR SULFIDE SIDE CHAIN THAT ENABLES THE ADDITIVE TO BE SOLUBLE IN FULLY FORMULATED CRANKCASE OIL BASED ON MINERAL AND GROUP II, III, AND IV BASE OILS | CK WITCO CORPORATION | 2001-02-13 | — | — | US | disclosed |
| US-6187722-B1 | Imidazole thione additives for lubricants | UNIROYAL CHEMICAL COMPANY, INC. | 2001-02-13 | — | — | US | disclosed |
| WO-2001007543-A1 | IMIDAZOLE THIONE ADDITIVES FOR LUBRICANTS | UNIROYAL CHEMICAL COMPANY, INC. (US) | 2001-02-01 | — | — | WO | disclosed |
| WO-2000053703-A1 | CYCLIC THIOUREA ADDITIVES FOR LUBRICANTS | UNIROYAL CHEMICAL COMPANY, INC. (US) | 2000-09-14 | — | — | WO | disclosed |
| US-5935913-A | EXTREME PRESSURE LUBRICANTS; ASHLESS AND NONPHOSPHORUS, ANTIWEAR, ANTIFATIGUE | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1999-08-10 | — | — | US | disclosed |
| EP-0039440-B1 | MEDICINES CONTAINING SUBSTITUTED BENZOTHIAZOL-2-(3H)-ONES | Dr. Karl Thomae GmbH (DE) | 1983-06-22 | — | — | EP | disclosed |
| US-4353919-A | Analgesic and antipyretic pharmaceutical compositions containing a benzothiazol-2(3H)-one | DR. KARL THOMAE GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1982-10-12 | — | — | US | disclosed |
| EP-0039818-A1 | Substituted 2-(3H)-benzothiazolones, processes for their preparation, their utilization in the preparation of medicines and medicines containing them | Dr. Karl Thomae GmbH (DE) | 1981-11-18 | — | — | EP | disclosed |
| EP-0039440-A1 | Medicines containing substituted benzothiazol-2-(3H)-ones | Dr. Karl Thomae GmbH (DE) | 1981-11-11 | — | — | EP | disclosed |