Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 4/20 | 0.46 |
| ▸ | CES2 | O00748 | 7/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 8/20 | 0.36 |
| ▸ | FAAH | O00519 | 5/20 | 0.36 |
| ▸ | PLA2G6 | O60733 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7839954 | 0.98 | EPHX1 (0.48) | EPHX1CES2TP53GMNNPOLB | |
| SCHEMBL199561 | 0.98 | EPHX1 (0.48) | EPHX1CES2TP53GMNNPOLB | |
| SCHEMBL28760871 | 0.98 | EPHX1 (0.48) | EPHX1CES2TP53GMNNPOLB | |
| SCHEMBL27347625 | 0.98 | EPHX1 (0.48) | EPHX1CES2TP53GMNNPOLB | |
| SCHEMBL11544996 | 0.98 | EPHX1 (0.48) | EPHX1CES2TP53GMNNPOLB | |
| SCHEMBL4611729 | 0.98 | EPHX1 (0.48) | EPHX1CES2TP53GMNNPOLB | |
| SCHEMBL8777414 | 0.98 | EPHX1 (0.48) | EPHX1CES2TP53GMNNPOLB | |
| SCHEMBL28331671 | 0.98 | EPHX1 (0.48) | EPHX1CES2TP53GMNNPOLB | |
| Hydrochloric Acid SCHEMBL10531008 | 0.96 | EPHX1 (0.47) | EPHX1CES2TP53GMNNPOLB | |
| SCHEMBL946019 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102408392-A | Green preparation method of 2- (N, N-disubstituted amino) -4-thiazolinone in water phase | UNIV ZHEJIANG | 2012-04-11 | — | — | CN | claimed |
| CN-110234722-A | Two-part adhesive composition | 株式会社LG化学 | 2019-09-13 | — | — | CN | disclosed |
| CN-108633280-A | The crosslinked foams manufactured by ethylene/alpha-olefin interpolymers | 陶氏环球技术有限责任公司 | 2018-10-09 | — | — | CN | disclosed |
| US-9073835-B2 | N-acylthiourea and N-acylurea inhibitors of the Hedgehog protein signalling pathway | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2015-07-07 | — | — | US | disclosed |
| US-20140371216-A1 | PURINONE DERIVATIVES AS HM74A AGONISTS | INCYTE CORPORATION (US) | 2014-12-18 | — | — | US | disclosed |
| US-8703783-B2 | Purinone derivatives as HM74A agonists | INCYTE CORPORATION (US) | 2014-04-22 | — | — | US | disclosed |
| CN-101874030-B | Pyrrolidines and piperidines as orexin receptor antagonists | ACTELION PHARMACEUTICALS LTD | 2012-11-14 | — | — | CN | disclosed |
| US-8288411-B2 | Pyrrolidines and piperidines as orexin receptor antagonists | ACTELION PHARMACEUTICALS LTD. (CH) | 2012-10-16 | — | — | US | disclosed |
| CN-102408392-A | Green preparation method of 2- (N, N-disubstituted amino) -4-thiazolinone in water phase | UNIV ZHEJIANG | 2012-04-11 | — | — | CN | disclosed |
| US-20120035172-A1 | Purinone Derivatives as HM74A Agonists | INCYTE CORPORATION (US) | 2012-02-09 | — | — | US | disclosed |
| US-4444872-A | CYAN PHENOLIC COUPLER | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1984-04-24 | — | — | US | disclosed |
| EP-0099234-A2 | Silver halide color photographic light-sensitive material | KONICA CORPORATION (JP) | 1984-01-25 | — | — | EP | disclosed |
| EP-0082732-A2 | A blocked magenta dye forming coupler | KONICA CORPORATION (JP) | 1983-06-29 | — | — | EP | disclosed |
| US-4378366-A | HYPOTENSIVE AND CARDIOTONIC AGENTS; ADRENERGIC STIMULANTS | SCIENCE UNION ET CIE (FR) | 1983-03-29 | — | — | US | disclosed |
| EP-0073146-A1 | Method and material for the formation of silver halide color photographic image | KONICA CORPORATION (JP) | 1983-03-02 | — | — | EP | disclosed |
| US-4356258-A | AN ACYLACETANILIDE DERIVATIVE; IMAGE PRESERVATION | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1982-10-26 | — | — | US | disclosed |
| US-4268620-A | Method of processing of light-sensitive silver halide photographic material | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1981-05-19 | — | — | US | disclosed |
| US-4221864-A | CONTRAST, SENSITIZERS | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1980-09-09 | — | — | US | disclosed |
| US-4210715-A | TETRAZOLIUM COMPOUND AND SENSITIZING DYE | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1980-07-01 | — | — | US | disclosed |
| US-4169733-A | PRETREATMENT WITH NITROGEN HETEROCYCLE SUBSTITUTED WITH MERCAPTO, THIOKETONE OR THIOETHER GROUP OF SILVER HALIDE EMULSION CONTAINING A TETRAZOLIUM COMPOUND | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1979-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140371216-A1 | PURINONE DERIVATIVES AS HM74A AGONISTS | GPR84, P2RY1, ADRA1A | EPHX1 676/4885CES2 3430/4885TP53 2735/4885 |
| US-20120035172-A1 | Purinone Derivatives as HM74A Agonists | GPR84, P2RY1, ADRA1A | EPHX1 676/4885CES2 3430/4885TP53 2735/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.