SCHEMBL789713

SCHEMBL789713

CCCCCSNC(=O)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.47
GMNN O75496 1/20 0.47
TP53 P04637 1/20 0.47
POLB P06746 1/20 0.47
MAPT P10636 1/20 0.47
THRB P10828 1/20 0.47
CYP2C9 P11712 1/20 0.47
BLM P54132 1/20 0.47
CES2 O00748 2/20 0.42
AKR1B1 P15121 1/20 0.41
GPR84 Q9NQS5 7/20 0.39
PPARG P37231 7/20 0.39
PPARD Q03181 7/20 0.39
PPARA Q07869 7/20 0.39
HDAC11 Q96DB2 5/20 0.39
TSHR P16473 4/20 0.39
PTPN1 P18031 3/20 0.39
ALDH1A1 P00352 2/20 0.39
TLR2 O60603 2/20 0.39
TDP1 Q9NUW8 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10529861 0.98 HSD17B10 (0.50) HSD17B10GMNNTP53POLBMAPT
SCHEMBL6907432 0.98 HSD17B10 (0.50) HSD17B10GMNNTP53POLBMAPT
SCHEMBL8207874 0.93
Carbamic Acid SCHEMBL29232548 0.92 EPHX1 (0.46) HSD17B10GMNNTP53POLBMAPT
SCHEMBL7496380 0.83 HSD17B10 (0.44) HSD17B10GMNNTP53POLBMAPT
SCHEMBL1276540 0.82 CES2 (0.47) HSD17B10GMNNTP53POLBMAPT
SCHEMBL11293412 0.80 CES2 (0.45) HSD17B10GMNNTP53POLBMAPT
SCHEMBL561899 0.80 EPHX1 (0.46) HSD17B10GMNNTP53POLBMAPT
SCHEMBL368268 0.79 EPHX1 (0.40) HSD17B10GMNNTP53POLBMAPT
SCHEMBL11305316 0.78 CES2 (0.44) HSD17B10GMNNTP53POLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020053353-A1 ELECTROCHEMICAL SYNTHESIS OF S-ARYLTHIOCARBAMATES UNIVERSITÄT ROSTOCK (DE) 2020-03-19 WO claimed
EP-2436056-B1 Electronic device comprising organic crosslinkable dielectrics and method of preparation thereof BASF SE (DE) 2016-08-03 EP claimed
EP-2403842-B1 CHIRAL DISULFONIMIDES STUDIENGESELLSCHAFT KOHLE MBH (DE) 2016-06-29 EP claimed
US-9079869-B2 Chiral disulfonimides STUDIENGESELLSCHAFT KOHLE MBH (DE) 2015-07-14 US claimed
CN-102804439-B Crosslinkable dielectrics and methods of making and using the same BASF SE 2015-05-27 CN claimed
US-8853820-B2 Crosslinkable dielectrics and methods of preparation and use thereof BASF SE (DE) 2014-10-07 US claimed
CN-102804439-A Crosslinkable dielectrics and methods of making and using the same BASF SE 2012-11-28 CN claimed
US-20120068314-A1 CROSSLINKABLE DIELECTRICS AND METHODS OF PREPARATION AND USE THEREOF POLYERA CORPORATION (US) 2012-03-22 US claimed
US-20110313150-A1 CHIRAL DISULFONIMIDES STUDIENGESELLSCHAFT KOHLE MBH (DE) 2011-12-22 US claimed
EP-1042282-A1 METHOD FOR PREPARING AROMATIC THIOLS AND DERIVATIVES, REAGENTS, INTERMEDIATE PRODUCTS AND METHOD FOR OBTAINING THEM RHODIA CHIMIE (FR) 2000-10-11 EP claimed
WO-1999032440-A1 METHOD FOR PREPARING AROMATIC THIOLS AND DERIVATIVES, REAGENTS, INTERMEDIATE PRODUCTS AND METHOD FOR OBTAINING THEM RHODIA CHIMIE (FR) 1999-07-01 WO claimed
WO-2020053353-A1 ELECTROCHEMICAL SYNTHESIS OF S-ARYLTHIOCARBAMATES UNIVERSITÄT ROSTOCK (DE) 2020-03-19 WO disclosed
WO-2020053353-A1 ELECTROCHEMICAL SYNTHESIS OF S-ARYLTHIOCARBAMATES UNIVERSITÄT ROSTOCK (DE) 2020-03-19 WO disclosed
EP-2436056-B1 Electronic device comprising organic crosslinkable dielectrics and method of preparation thereof BASF SE (DE) 2016-08-03 EP disclosed
US-9079869-B2 Chiral disulfonimides STUDIENGESELLSCHAFT KOHLE MBH (DE) 2015-07-14 US disclosed
US-4745128-A INSECTICIDES, MITICIDES INNOFINANCE ALTALANOS INNOVACIOS PENZINTEZET (HU) 1988-05-17 US disclosed
EP-0251552-A2 Process for producing aminothiophenols and their derivatives CELANESE CORPORATION (US) 1988-01-07 EP disclosed
WO-1987007114-A1 HERBICIDAL SULFONAMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1987-12-03 WO disclosed
EP-0212779-A2 Herbicidal sulfonamides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1987-03-04 EP disclosed
EP-0166516-A2 Novel phenyl-subsituted sulfonamides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1986-01-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110313150-A1 CHIRAL DISULFONIMIDES STS, SUDS3, SF1 HSD17B10 1302/4885GMNN 1425/4885TP53 4111/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.