Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | METAP1 | P53582 | 2/20 | 0.31 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6285756 | 0.83 | CA2 (0.38) | LMNATDP1SPHK1CYP3A4FDPS | |
| SCHEMBL2838533 | 0.82 | — | — | |
| SCHEMBL5053889 | 0.82 | TSHR (0.35) | TSHRLMNACHRM1AKR1A1CHRM3 | |
| Hydrochloric Acid SCHEMBL27486768 | 0.80 | TSHR (0.39) | TSHRLMNACHRM1AKR1A1CHRM3 | |
| SCHEMBL6367270 | 0.80 | — | — | |
| SCHEMBL29394109 | 0.78 | TSHR (0.32) | TSHRLMNA | |
| SCHEMBL10892982 | 0.76 | TSHR (0.36) | TSHRLMNA | |
| SCHEMBL14949496 | 0.76 | FDPS (0.34) | TSHRLMNAFDPS | |
| SCHEMBL4606703 | 0.76 | TSHR (0.31) | TSHRLMNA | |
| SCHEMBL159038 | 0.75 | TSHR (0.53) | TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8829145-B2 | Water-stable catalysts for polyurethane manufacture | DORF KETAL CHEMICALS (INDIA) PVT. LTD. (IN) | 2014-09-09 | — | — | US | disclosed |
| US-20100249359-A1 | WATER-STABLE CATALYSTS FOR POLYURETHANE MANUFACTURE | JOHNSON MATTHEY PLC (GB) | 2010-09-30 | — | — | US | disclosed |