Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6367270 | 0.79 | — | — | |
| SCHEMBL20796785 | 0.79 | TSHR (0.33) | TSHRLMNA | |
| SCHEMBL27224848 | 0.79 | TSHR (0.33) | TSHRLMNA | |
| SCHEMBL934067 | 0.79 | TSHR (0.33) | TSHRLMNA | |
| SCHEMBL29223272 | 0.77 | TSHR (0.32) | TSHRLMNA | |
| SCHEMBL2838533 | 0.76 | — | — | |
| SCHEMBL5053889 | 0.76 | TSHR (0.35) | TSHRLMNA | |
| SCHEMBL3683086 | 0.76 | TSHR (0.35) | TSHRLMNA | |
| Alcohol SCHEMBL11217558 | 0.75 | TSHR (0.35) | TSHRLMNA | |
| SCHEMBL18422068 | 0.75 | CHRM1 (0.33) | TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7374580-B2 | Dyeing compositions comprising A 1,2-indandione derivative | L'OREAL S.A. (FR) | 2008-05-20 | — | — | US | claimed |
| US-7367993-B2 | Dyeing compositions comprising at least one 1,3-indandione derivative | L'OREAL S.A. (FR) | 2008-05-06 | — | — | US | claimed |
| EP-1502580-B1 | Use in dyeing of aromatic polycyclic vicinal triones with condensed cycles | OREAL (FR) | 2008-01-23 | — | — | EP | claimed |
| EP-1500387-B1 | Use of ninhydrin derivatives for dyeing | OREAL (FR) | 2008-01-09 | — | — | EP | claimed |
| US-7192455-B2 | Process for dyeing keratin fibers with at least one ninhydrin derivative | L'OREAL S.A. (FR) | 2007-03-20 | — | — | US | claimed |
| US-7182790-B2 | Use of at least one ninhydrin derivative for dyeing | L'OREAL S.A. (FR) | 2007-02-27 | — | — | US | claimed |
| US-7182791-B2 | Composition and method of dyeing keratin fibers comprising at least one heteroalkyl group comprising at least one ninhydrin derivative | L'OREAL S.A. (FR) | 2007-02-27 | — | — | US | claimed |
| US-7179304-B2 | Process for dyeing keratin fibers with at least one polycyclic aromatic vicinal trione | L'OREAL S.A. (FR) | 2007-02-20 | — | — | US | claimed |
| US-7179306-B2 | Process for dying keratin fibers comprising at least one aryl or aryloxy substitutent-based ninhydrin derivative | L'OREAL S.A. (FR) | 2007-02-20 | — | — | US | claimed |
| US-7179305-B2 | Process for dyeing keratin fibers with ninhydrin compounds comprising one or more fused rings | L'OREAL S.A. (FR) | 2007-02-20 | — | — | US | claimed |
| US-20050050653-A1 | Process for dyeing keratin fibers with ninhydrin compounds comprising one or more fused rings | L'OREAL S.A. (FR) | 2005-03-10 | — | — | US | claimed |
| US-20050050652-A1 | Process for dyeing keratin fibers with at least one polycyclic aromatic vicinal trione | L'OREAL S.A. (FR) | 2005-03-10 | — | — | US | claimed |
| US-20050050654-A1 | Process for dyeing keratin fibers with at least one ninhydrin derivative | L'OREAL S.A. (FR) | 2005-03-10 | — | — | US | claimed |
| US-20050050651-A1 | Use of at least one ninhydrin derivative for dyeing | L'OREAL S.A. (FR) | 2005-03-10 | — | — | US | claimed |
| EP-1502580-A1 | Use in dyeing of aromatic polycyclic vicinal triones with condensed cycles | L'OREAL (FR) | 2005-02-02 | — | — | EP | claimed |
| EP-1500387-A1 | Use of ninhydrin derivatives for dyeing | L'OREAL (FR) | 2005-01-26 | — | — | EP | claimed |
| EP-0695162-B1 | DYES CONTAINING ISATIN FOR KERATIN-CONTAINING FIBRES | HENKEL KGAA (DE) | 1997-06-18 | — | — | EP | claimed |
| US-5616150-A | HAIR DYES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1997-04-01 | — | — | US | claimed |
| EP-0695162-A1 | DYES CONTAINING ISATIN FOR KERATIN-CONTAINING FIBRES | HENKEL KGAA (DE) | 1996-02-07 | — | — | EP | claimed |
| WO-1994024988-A1 | DYES CONTAINING ISATIN FOR KERATIN-CONTAINING FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1994-11-10 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050050653-A1 | Process for dyeing keratin fibers with ninhydrin compounds comprising one or more fused rings | KRT18, NISCH, JUP | TSHR 4411/4885LMNA 507/4885 |
| US-20050050652-A1 | Process for dyeing keratin fibers with at least one polycyclic aromatic vicinal trione | KRT18, HKDC1, JUP | TSHR 3793/4885LMNA 1336/4885 |
| US-20050050654-A1 | Process for dyeing keratin fibers with at least one ninhydrin derivative | KRT18, DSG1, ACR | TSHR 4850/4885LMNA 471/4885 |
| US-20050050651-A1 | Use of at least one ninhydrin derivative for dyeing | NISCH, NPM1, NCDN | TSHR 4677/4885LMNA 3027/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.