Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3683303 | 0.68 | NPC1 (0.42) | NPC1RAB9APNMTPGRHTR7 | |
| Hydrochloric Acid SCHEMBL7272255 | 0.68 | PNMT (0.36) | NPC1RAB9APNMTPGRHTR7 | |
| SCHEMBL3683305 | 0.66 | NPC1 (0.37) | NPC1RAB9APNMTPGRHTR7 | |
| Hydrochloric Acid SCHEMBL7634675 | 0.64 | NPC1 (0.40) | NPC1RAB9APNMTHTR7HTR2B | |
| SCHEMBL7272264 | 0.64 | PNMT (0.35) | NPC1RAB9APNMTPGRHTR7 | |
| Hydrochloric Acid SCHEMBL3385861 | 0.63 | PNMT (0.52) | NPC1RAB9APNMTPGRHTR7 | |
| Hydrochloric Acid SCHEMBL30274953 | 0.63 | PNMT (0.52) | NPC1RAB9APNMTPGRHTR7 | |
| SCHEMBL30103334 | 0.62 | PNMT (0.63) | NPC1RAB9APNMTPGRHTR7 | |
| SCHEMBL524602 | 0.62 | PNMT (0.63) | NPC1RAB9APNMTPGRHTR7 | |
| SCHEMBL7634726 | 0.62 | NPC1 (0.40) | NPC1RAB9APNMTHTR7HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7687566-B2 | Propylene resin composition and molding thereof | MITSUBISHI CHEMICAL CORPORATION (JP) | 2010-03-30 | — | — | US | disclosed |
| US-20070238828-A1 | Propylene Resin Composition and Molding Thereof | MITSUBISHI CHEMICAL CORPORATION (JP) | 2007-10-11 | — | — | US | disclosed |
| EP-1726619-A1 | PROPYLENE RESIN COMPOSITION AND MOLDING THEREOF | Mitsubishi Chemical Corporation (JP) | 2006-11-29 | — | — | EP | disclosed |