Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29911898 | 0.76 | PNMT (0.36) | PNMTNPC1RAB9ADRD2DRD4 | |
| Hydrochloric Acid SCHEMBL673539 | 0.76 | PNMT (0.36) | PNMTNPC1RAB9ADRD2DRD4 | |
| Hydrochloric Acid SCHEMBL7265194 | 0.74 | PNMT (0.35) | PNMTNPC1RAB9APGR | |
| Hydrochloric Acid SCHEMBL7269963 | 0.73 | PNMT (0.32) | PNMTNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL29556412 | 0.72 | PNMT (0.41) | PNMTNPC1RAB9APGRDRD2 | |
| Hydrochloric Acid SCHEMBL29479988 | 0.71 | PNMT (0.50) | PNMTNPC1RAB9APGRDRD2 | |
| Hydrochloric Acid SCHEMBL618215 | 0.71 | PNMT (0.50) | PNMTNPC1RAB9APGRDRD2 | |
| Hydrochloric Acid SCHEMBL30525928 | 0.71 | PNMT (0.30) | PNMTNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL2484271 | 0.71 | PNMT (0.32) | PNMTNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL7272238 | 0.70 | KDM4E (0.33) | RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1270615-A1 | ETHYLENE-BASE COPOLYMERS, PROCESS FOR PRODUCING THE SAME AND LUBRICATING OIL COMPOSITIONS CONTAINING THE SAME | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 2003-01-02 | — | — | EP | disclosed |