Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | UBE2N | P61088 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3681473 | 0.88 | CHRM1 (0.44) | MEN1KMT2ACYP2D6P2RX7SLC6A2 | |
| SCHEMBL3688675 | 0.75 | CHRM1 (0.43) | RAB9ANPC1P2RX7SLC6A2SLC6A4 | |
| SCHEMBL19574651 | 0.70 | NPC1 (0.49) | MEN1KMT2ARAB9ANPC1PARP14 | |
| SCHEMBL3800845 | 0.70 | MEN1 (0.37) | MEN1KMT2ACYP2D6HSP90AA1UBE2N | |
| SCHEMBL22372868 | 0.69 | MEN1 (0.41) | MEN1KMT2ACYP2D6GAASLC6A2 | |
| SCHEMBL30545023 | 0.69 | NPC1 (0.48) | MEN1KMT2ARAB9ANPC1PARP14 | |
| SCHEMBL22800944 | 0.68 | POLB (0.48) | MEN1KMT2AGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL17087832 | 0.67 | HSD17B10 (0.64) | MEN1KMT2AKDM4EHTT | |
| SCHEMBL15297063 | 0.67 | LMNA (0.47) | MEN1KMT2ARAB9ANPC1GAA | |
| SCHEMBL5817988 | 0.66 | GNAI3 (0.39) | MEN1KMT2ACYP2D6GAASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2187748-A2 | FUNGICIDAL COMPOUNDS AND MIXTURES | E. I. du Pont de Nemours and Company (US) | 2010-05-26 | — | — | EP | claimed |
| WO-2009055514-A2 | FUNGICIDAL MIXTURES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-04-30 | — | — | WO | claimed |
| EP-2187748-A2 | FUNGICIDAL COMPOUNDS AND MIXTURES | E. I. du Pont de Nemours and Company (US) | 2010-05-26 | — | — | EP | disclosed |
| WO-2009055514-A2 | FUNGICIDAL MIXTURES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-04-30 | — | — | WO | disclosed |