Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | UBE2N | P61088 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3681467 | 0.76 | KMT2A (0.44) | MEN1KMT2AALDH1A1LMNATSHR | |
| SCHEMBL13170122 | 0.71 | LMNA (0.38) | MEN1KMT2ANPC1ALDH1A1LMNA | |
| SCHEMBL3683328 | 0.70 | MEN1 (0.45) | MEN1KMT2ACYP2D6NPC1RAB9A | |
| SCHEMBL3750240 | 0.70 | MDM2 (0.41) | MEN1KMT2AALDH1A1MDM2TSHR | |
| SCHEMBL16308869 | 0.64 | LMNA (0.41) | MEN1KMT2ANPC1ALDH1A1LMNA | |
| SCHEMBL5817988 | 0.62 | GNAI3 (0.39) | MEN1KMT2ACYP2D6ALDH1A1LMNA | |
| SCHEMBL3681473 | 0.61 | CHRM1 (0.44) | MEN1KMT2ACYP2D6ALDH1A1LMNA | |
| SCHEMBL13170136 | 0.61 | LMNA (0.38) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL2364801 | 0.59 | GAA (0.41) | MEN1KMT2AALDH1A1TSHRMAPK1 | |
| SCHEMBL28327728 | 0.59 | MEN1 (0.66) | MEN1KMT2ACYP2D6NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2187748-A2 | FUNGICIDAL COMPOUNDS AND MIXTURES | E. I. du Pont de Nemours and Company (US) | 2010-05-26 | — | — | EP | disclosed |
| WO-2009055514-A2 | FUNGICIDAL MIXTURES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-04-30 | — | — | WO | disclosed |