SCHEMBL368334

SCHEMBL368334

C=CCOC(=Cc1ccccc1)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.51
ALDH1A1 P00352 2/20 0.45
TSHR P16473 2/20 0.45
HSD17B10 Q99714 2/20 0.45
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
PKM P14618 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
KDM4E B2RXH2 1/20 0.44
LMNA P02545 1/20 0.44
GAA P10253 1/20 0.44
MAPT P10636 1/20 0.44
MAPK1 P28482 1/20 0.44
AKR1C3 P42330 1/20 0.43
CYP2C9 P11712 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
AKR1C1 Q04828 1/20 0.42
ALOX12 P18054 1/20 0.40
RHOA P61586 1/20 0.39
CASP1 P29466 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7197167 0.87 CYP3A4 (0.49) CYP3A4ALDH1A1TSHRHSD17B10MEN1
SCHEMBL4064482 0.83 MEN1 (0.42) CYP3A4ALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL17183868 0.83 CYP3A4 (0.41) CYP3A4ALDH1A1TSHRHSD17B10MEN1
SCHEMBL252039 0.81 MEN1 (0.47) CYP3A4ALDH1A1TSHRHSD17B10MEN1
SCHEMBL8219793 0.81 MEN1 (0.64) CYP3A4ALDH1A1TSHRHSD17B10MEN1
SCHEMBL924566 0.80 MEN1 (0.49) CYP3A4ALDH1A1TSHRMEN1KMT2A
SCHEMBL528920 0.80 MEN1 (0.49) CYP3A4ALDH1A1TSHRMEN1KMT2A
SCHEMBL7024675 0.79 CYP3A4 (0.51) CYP3A4ALDH1A1TSHRHSD17B10MEN1
SCHEMBL2229690 0.79 MEN1 (0.66) CYP3A4ALDH1A1TSHRMEN1KMT2A
SCHEMBL6637645 0.79 MEN1 (0.47) CYP3A4ALDH1A1TSHRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6066696-A Optical alignment composition, alignment layer formed using the same and LCD having the alignment layer SAMSUNG DISPLAY DEVICES CO. LTD. (KR) 2000-05-23 US claimed
JP-10232400-A None JP disclosed
US-10781373-B2 Photoalignment film forming composition and LCD devices derived therefrom PROMERUS, LLC (US) 2020-09-22 US disclosed
WO-2018148479-A1 PHOTOALIGNMENT FILM FORMING COMPOSITION AND LCD DEVICES DERIVED THEREFROM PROMERUS, LLC (US) 2018-08-16 WO disclosed
US-20180223190-A1 PHOTOALIGNMENT FILM FORMING COMPOSITION AND LCD DEVICES DERIVED THEREFROM PROMERUS, LLC (US) 2018-08-09 US disclosed
US-9952364-B2 Optical film and display device comprising the same LG CHEM, LTD. (KR) 2018-04-24 US disclosed
US-9791745-B2 Photoalignment polyimide copolymer and liquid crystal alignment layer LG CHEM, LTD. (KR) 2017-10-17 US disclosed
US-20160222147-A1 PHOTOREACTIVE COPOLYMER AND ALIGNMENT LAYER COMPRISING THE SAME LG CHEM, LTD. (KR) 2016-08-04 US disclosed
EP-3018158-A1 PHOTO-REACTIVE COPOLYMER AND ALIGNMENT LAYER COMPRISING SAME LG Chem, Ltd. (KR) 2016-05-11 EP disclosed
EP-2592096-B1 PHOTOREACTIVE NORBORNENE-BASED COPOLYMER, A PRODUCTION METHOD FOR THE SAME AND AN ALIGNMENT LAYER COMPRISING THE SAME LG CHEMICAL LTD (KR) 2016-03-02 EP disclosed
US-6055103-A Passive polarisation modulating optical element and method of making such an element SHARP KABUSHIKI KAISHA (JP) 2000-04-25 US disclosed
US-6046849-A Parallax barrier, display, passive polarisation modulating optical element and method of making such an element SHARP KABUSHIKI KAISHA (JP) 2000-04-04 US disclosed
US-5976640-A Optical alignment composition, alignment layer formed using the same and LCD having the alignment layer SAMSUNG DISPLAY DEVICES CO., LTD. (KR) 1999-11-02 US disclosed
US-5946064-A Alignment layer, method for forming alignment layer and LCD having the same SAMSUNG DISPLAY DEVICES CO., LTD. (KR) 1999-08-31 US disclosed
US-5925423-A Optical alignment polymer, alignment layer formed using the same and liquid crystal display device having the alignment layer SAMSUNG DISPLAY DEVICES CO., LTD (KR) 1999-07-20 US disclosed
EP-0887666-A2 Passive polarisation modulating optical element and method of making such an element Sharp Kabushiki Kaisha (JP) 1998-12-30 EP disclosed
EP-0887692-A2 Method of making a spatial light modulation Sharp Kabushiki Kaisha (JP) 1998-12-30 EP disclosed
JP-H10232400-A OPTICAL ORIENTING COMPOSITION, ALIGNMENT LAYER FORMED FROM THAT COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT EQUIPPED WITH THAT ALIGNMENT LAYER SAMSUNG DISPLAY DEVICES CO LTD 1998-09-02 JP disclosed
EP-0829744-A2 Parallax barrier and display passive polarisation modulating optical element & method of making such an element SHARP KABUSHIKI KAISHA (JP) 1998-03-18 EP disclosed
US-4720559-A Certain 2,3-dihydobenzofuran-3-yl acetic acids and their method of preparation EASTMAN KODAK COMPANY (US) 1988-01-19 US disclosed