SCHEMBL528920

SCHEMBL528920

O=C(O)C(=Cc1ccccc1)OCO

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
AKR1C3 P42330 2/20 0.47
CYP3A4 P08684 1/20 0.46
CYP2C9 P11712 1/20 0.46
AKR1C1 Q04828 1/20 0.46
RECQL P46063 1/20 0.41
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
TP53 P04637 1/20 0.40
HTT P42858 1/20 0.40
FBP1 P09467 1/20 0.39
LMNA P02545 1/20 0.39
NR1I2 O75469 1/20 0.39
ALDH1A1 P00352 2/20 0.38
TSHR P16473 1/20 0.38
HAO1 Q9UJM8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11683148 0.85 MEN1 (0.46) MEN1KMT2AAKR1C3CYP3A4CYP2C9
SCHEMBL924566 0.85 MEN1 (0.49) MEN1KMT2AAKR1C3CYP3A4CYP2C9
SCHEMBL6637645 0.83 MEN1 (0.47) MEN1KMT2AAKR1C3CYP3A4CYP2C9
SCHEMBL2229690 0.83 MEN1 (0.66) MEN1KMT2AAKR1C3CYP3A4CYP2C9
SCHEMBL11685413 0.82 MEN1 (0.44) MEN1KMT2AAKR1C3CYP3A4CYP2C9
SCHEMBL10661140 0.81 LMNA (0.56) MEN1KMT2AAKR1C3CYP3A4CYP2C9
SCHEMBL12500129 0.81 LMNA (0.56) MEN1KMT2AAKR1C3CYP3A4CYP2C9
SCHEMBL5698609 0.81 MEN1 (0.42) MEN1KMT2AAKR1C3CYP3A4CYP2C9
SCHEMBL17311135 0.80 AKR1C1 (0.46) MEN1KMT2AAKR1C3CYP3A4CYP2C9
SCHEMBL368334 0.80 CYP3A4 (0.51) MEN1KMT2AAKR1C3CYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10023689-B2 Functional biodegradable polymers THE UNIVERSITY OF AKRON 2018-07-17 US claimed
US-20160229952-A1 FUNCTIONAL BIODEGRADABLE POLYMERS NATIONAL SCIENCE FOUNDATION 2016-08-11 US claimed
US-20130184429-A1 FUNCTIONAL BIODEGRADABLE POLYMERS THE UNIVERSITY OF AKRON (US) 2013-07-18 US claimed
EP-2598552-A1 FUNCTIONAL BIODEGRADABLE POLYMERS University Of Akron (US) 2013-06-05 EP claimed
WO-2012015481-A1 FUNCTIONAL BIODEGRADABLE POLYMERS UNIVERSITY OF AKRON (US) 2012-02-02 WO claimed
US-20090130739-A1 Deactivation of mineral encapsulated nanobacteria AMERICAN STERILIZER COMPANY (US) 2009-05-21 US claimed
US-12005089-B2 CVS transplantation for treatment of bacterial vaginosis THE JOHNS HOPKINS UNIVERSITY (US) 2024-06-11 US disclosed
WO-2022108368-A9 CONJUGATE COMPRISING SIALIC ACID OR DERIVATIVE THEREOF BONDED TO SURFACE OF DENDRIMER CORE, AND USE THEREOF 주식회사 나노메디카 2022-08-18 WO disclosed
WO-2022108368-A1 CONJUGATE COMPRISING SIALIC ACID OR DERIVATIVE THEREOF BONDED TO SURFACE OF DENDRIMER CORE, AND USE THEREOF 주식회사 나노메디카 2022-05-27 WO disclosed
US-10023689-B2 Functional biodegradable polymers THE UNIVERSITY OF AKRON 2018-07-17 US disclosed
US-20160279182-A1 CVS TRANSPLANTATION FOR TREATMENT OF BACTERIAL VAGINOSIS THE JOHNS HOPKINS UNIVERSITY 2016-09-29 US disclosed
US-20160229952-A1 FUNCTIONAL BIODEGRADABLE POLYMERS NATIONAL SCIENCE FOUNDATION 2016-08-11 US disclosed
US-20130184429-A1 FUNCTIONAL BIODEGRADABLE POLYMERS THE UNIVERSITY OF AKRON (US) 2013-07-18 US disclosed
WO-2012015481-A1 FUNCTIONAL BIODEGRADABLE POLYMERS UNIVERSITY OF AKRON (US) 2012-02-02 WO disclosed
EP-2222319-A2 TOPICAL DRUGS FOR USE IN ANTIFUNGAL THERAPY Bayer Consumer Care AG (CH) 2010-09-01 EP disclosed
WO-2009062746-A2 TOPICAL DRUGS FOR USE IN ANTIFUNGAL THERAPY BAYER CONSUMER CARE AG (CH) 2009-05-22 WO disclosed
US-20090130739-A1 Deactivation of mineral encapsulated nanobacteria AMERICAN STERILIZER COMPANY (US) 2009-05-21 US disclosed
EP-1917043-A2 DEACTIVATION OF MINERAL ENCAPSULATED NANOBACTERIA Steris, Inc. (US) 2008-05-07 EP disclosed
WO-2007145608-A2 DEACTIVATION OF MINERAL ENCAPSULATED NANOBACTERIA STERIS, INC. (US) 2007-12-21 WO disclosed
US-20060270571-A1 Deactivation of mineral encapsulated nanobacteria AMERICAN STERILIZER COMPANY 2006-11-30 US disclosed