Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20596721 | 0.86 | MCL1 (0.45) | MEN1KMT2AAKR1C3CYP3A4CYP2C9 | |
| SCHEMBL528920 | 0.83 | MEN1 (0.49) | MEN1KMT2AAKR1C3CYP3A4CYP2C9 | |
| SCHEMBL924566 | 0.83 | MEN1 (0.49) | MEN1KMT2AAKR1C3CYP3A4CYP2C9 | |
| SCHEMBL17311135 | 0.82 | AKR1C1 (0.46) | MEN1KMT2AAKR1C3CYP3A4CYP2C9 | |
| SCHEMBL2229690 | 0.81 | MEN1 (0.66) | MEN1KMT2AAKR1C3CYP3A4CYP2C9 | |
| SCHEMBL10661140 | 0.80 | LMNA (0.56) | MEN1KMT2AAKR1C3CYP3A4CYP2C9 | |
| SCHEMBL12500129 | 0.80 | LMNA (0.56) | MEN1KMT2AAKR1C3CYP3A4CYP2C9 | |
| SCHEMBL11683148 | 0.80 | MEN1 (0.46) | MEN1KMT2AAKR1C3CYP3A4CYP2C9 | |
| SCHEMBL4064482 | 0.80 | MEN1 (0.42) | MEN1KMT2AAKR1C3CYP3A4CYP2C9 | |
| SCHEMBL368334 | 0.79 | CYP3A4 (0.51) | MEN1KMT2AAKR1C3CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1474419-A1 | AMIDES OF AMINOALKYL-SUBSTITUTED AZETIDINES, PYRROLIDINES, PIPERIDINES AND AZEPANES | NOVO NORDISK A/S (DK) | 2004-11-10 | — | — | EP | disclosed |
| WO-2003064411-A1 | AMIDES OF AMINOALKYL-SUBSTITUTED AZETIDINES, PYRROLIDINES, PIPERIDINES AND AZEPANES | NOVO NORDISK A/S (DK) | 2003-08-07 | — | — | WO | disclosed |